DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr2 and cadm4

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_002939173.1	Gene:	cadm4 / 100488420	XenbaseID:	XB-GENE-992659	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	74/342 - (21%)
Similarity:	117/342 - (34%)	Gaps:	96/342 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 GNSIDDEREAEEQPPEETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHI 148
            |..:..|.:||                    |:|...|.||.|:|.:... |.|:..|:......
Frog    27 GTVVSQEVQAE--------------------NVTVVEGGTAEISCHLHQY-DGSIVVIQNPVRQT 70

  Fly   149 LTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDA 213
            |.........|.||::|... .|...:|:..|:..|.|.|.||:.||........|.||| |||.
Frog    71 LFFNGTRALKDTRFQLVEFT-QKVVKIHLSDAKLEDEGGYFCQLYTEDTHHQIATLTVIV-PPDN 133

  Fly   214 KAIIAGPTDLYVK----VGSSVTLTCHVKQPATSAQDIGPIYWYRG---------------PYIL 259
            ..:       .||    .|..:.|||  ..|.|  :....:.|||.               .:.:
Frog   134 PLV-------EVKEQAVEGGEIELTC--ISPRT--RPAATLRWYRDRKELKGFTSKQENGKTFSI 187

  Fly   260 TPFVAHPNDAAIDLQRISMEST----LAEKLQSRLRI-------ANAQ----LLDTG---NYTCM 306
            |..:....|...|...::.|::    ..:|.|::..:       ||.|    |:..|   |..|.
Frog   188 TNSIRFSVDRKDDRDIVTCEASHPALKGQKKQTQYELDVQFSPTANIQPSQSLVREGDELNLKCE 252

  Fly   307 PT-TAEAASVVVNVINDESPAAMQ--------KSRAIRTSGSM---------RSSRLVLLLAMVA 353
            .| ......::...:||..|...|        .|.:::.:|:.         |||...:|:....
Frog   253 VTGNPRPTEIIWTRLNDSLPERAQIQGDVLSFPSLSLQDNGTYSCQVSNKHGRSSDQYVLVVYDP 317

  Fly   354 SSVVR-------WLIGG 363
            .:::.       .:|||
Frog   318 GAIIEAQTQVPYAVIGG 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	26/92 (28%)
		Ig	116..192	CDD:299845	21/75 (28%)
		ig	220..306	CDD:278476	23/122 (19%)
		IG_like	220..306	CDD:214653	23/122 (19%)
cadm4	XP_002939173.1	Ig	37..127	CDD:299845	27/111 (24%)
		IG_like	37..127	CDD:214653	27/111 (24%)
		Ig2_Necl-4	147..226	CDD:143293	14/82 (17%)
		Ig_3	230..301	CDD:290638	14/70 (20%)
		IG_like	236..314	CDD:214653	15/77 (19%)
		4.1m	350..368	CDD:128590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I5030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050