DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and cd4-2.2

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001352989.1	Gene:	cd4-2.2 / 100334281	ZFINID:	ZDB-GENE-100922-127	Length:	515	Species:	Danio rerio

Alignment Length:	169	Identity:	39/169 - (23%)
Similarity:	63/169 - (37%)	Gaps:	61/169 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 TADSKDW---TLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKVG 228
            |||..:.   ||:|...:|||||:|.|     .:....:.|:|:              .::||.|
Zfish    90 TADKVNLYGDTLNVPRLEPRDSGVYSC-----TQSGKQYTLHVV--------------SVFVKPG 135

  Fly   229 ------SSVTLTCHVK-QPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDL--QRISMESTLAE 284
                  |.|.|.|::: .|.|..:      |.|          .|||...|.  |:|:::|..:.
Zfish   136 PVLIQSSDVELHCNIEGDPNTEVE------WLR----------PPNDQVHDAKHQKINLKSVSSS 184

  Fly   285 KLQSRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDE 323
                          |.|.:||.....:.:..:..|.|.:
Zfish   185 --------------DEGKWTCKVEDLKLSVTLTVVANHQ 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	14/41 (34%)
		Ig	116..192	CDD:299845	13/27 (48%)
		ig	220..306	CDD:278476	21/94 (22%)
		IG_like	220..306	CDD:214653	21/94 (22%)
cd4-2.2	NP_001352989.1	IG	45..119	CDD:214652	13/33 (39%)
		I-set	133..204	CDD:333254	21/100 (21%)
		IG	212..317	CDD:214652
		IG_like	345..416	CDD:214653
		IG_like	426..501	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910