DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	216	Identity:	51/216 - (23%)
Similarity:	89/216 - (41%)	Gaps:	50/216 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 SMAFRLNVIVTPPDAKAIIAG--PTDLYVKVGSSVTLTCHV--KQPATSAQDIGPIYW-YRGPYI 258
            |..|.|.|...|.:   |:..  |||.|:|.||::||||..  ..|||       |.| :.|..:
Zfish   215 SAPFNLTVSYGPEN---ILMNQFPTDTYLKKGSTLTLTCTADSNPPAT-------IQWVFNGVNL 269

  Fly   259 LTPFVAHPNDAAIDLQRISMESTLAEKLQSRLRIANAQLLDTGNYTCMPTTAEAASVV------V 317
            .:..|:.|.:..:        :.|.||             ::|||||:...|:....:      |
Zfish   270 PSNAVSSPANFTL--------NNLEEK-------------NSGNYTCVAYNAQTKRYIASRVAFV 313

  Fly   318 NVINDESPAAMQKSRAIRTSGSMRSSRLVLLLAMVASSVVRWLIGGQRIGSNSCHDSCSNLSTLH 382
            .|:...|...:..|.::..:|: .:..|....|...:..|.|:..|:.:..:|.....::.:::.
Zfish   314 TVVESLSGTNISSSTSLLIAGN-STVNLTCFAAAGRAETVEWVKDGKPLNPDSRIVFSADKTSVS 377

  Fly   383 INYCNLRAKITSHLK-EHRCL 402
            |:      |:....: |:|||
Zfish   378 ID------KVVKEDRGEYRCL 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	3/6 (50%)
		Ig	116..192	CDD:299845
		ig	220..306	CDD:278476	26/88 (30%)
		IG_like	220..306	CDD:214653	26/88 (30%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845
		IG_like	33..128	CDD:214653
		Ig	130..222	CDD:299845	3/6 (50%)
		IG_like	149..222	CDD:214653	3/6 (50%)
		I-set	233..315	CDD:254352	29/109 (27%)
		Ig_2	235..315	CDD:290606	29/107 (27%)
		IGc2	335..398	CDD:197706	12/65 (18%)
		Ig_2	427..494	CDD:290606
		IG_like	427..479	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910