DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and zgc:172133

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001121763.1	Gene:	zgc:172133 / 100003819	ZFINID:	ZDB-GENE-080204-48	Length:	396	Species:	Danio rerio

Alignment Length:	261	Identity:	57/261 - (21%)
Similarity:	96/261 - (36%)	Gaps:	54/261 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 NITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTY--------TSDERFKVVRTADSK 171
            :::...|.:..:...|.......::|...:.   ..|.|:.|        |..:||:.....||:
Zfish   129 SVSVMEGDSVTLCTGVQTNQSNRINWYFNKG---RIAEIIGYRRKVCADDTCPQRFRDRLKLDSQ 190

  Fly   172 DWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTD-----LYVKVGSSV 231
            ..:|.:......|||:|........||   ||:          ||:...|:     ..|..|.|:
Zfish   191 IGSLTIMKVSTEDSGLYTLLHRGREKI---FRV----------AILDSSTEENWKQKSVTEGESI 242

  Fly   232 TLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSR-----LR 291
            ||...:|   |:..|:  :.||.|..:|.......:....|.|....|....::|:..     |.
Zfish   243 TLDTPIK---TTPNDV--LKWYFGEILLAEITGDESQICEDAQCKDGEDEFRDRLKVNHSSGFLT 302

  Fly   292 IANAQLLDTGNYTCMPTT-----AEAASVVVNVINDESPAAMQKSRAIRTSGSMRSSRLVLLLAM 351
            |.|::..|:|.||.:..:     :.:.||:|..          ...::.|...|....|||||.:
Zfish   303 IMNSRKADSGEYTLLINSTSFYISRSFSVIVTF----------SGISLSTGIGMCVGVLVLLLLL 357

  Fly   352 V 352
            |
Zfish   358 V 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	20/98 (20%)
		Ig	116..192	CDD:299845	16/83 (19%)
		ig	220..306	CDD:278476	24/95 (25%)
		IG_like	220..306	CDD:214653	24/95 (25%)
zgc:172133	NP_001121763.1	IG_like	23..118	CDD:214653
		Ig	28..117	CDD:299845
		Ig	128..208	CDD:299845	15/81 (19%)
		IG_like	128..>208	CDD:214653	15/81 (19%)
		IG_like	235..333	CDD:214653	25/102 (25%)
		Ig	239..333	CDD:299845	24/98 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910