Protein Alignment ppk13 and SCNN1B

DIOPT Version :9

• Sequence 1: NP_001014495.1
• Gene: ppk13 / 3346226
• FlyBaseID: FBgn0053508
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_016879014.1
• Gene: SCNN1B / 6338
• HGNCID: 10600
• Length: 659
• Species: Homo sapiens
• Alignment Length: 603
• Identity: 114/603 - (18%)
• Similarity: 184/603 - (30%)
• Gaps: 240/603 - (39%)

  Fly     3 FSRVIEEYLKNSTLHGARFIV----DKDASWIERIFWVICLVA-SW------YASWLLIKASLSA 56
            :..::..|..|:..||.:.|:    .|.|.|.........||. .|      |.|| .:..|||.
Human    41 YKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSW-EVSVSLSV 104

  Fly    57 FENNAISFVVESSFRDWNTNFPAIIVCES------------KNMDRIQE-VAEQ----------- 97
                        .|:  ..:|||:.:|.:            |::|.:.| |.|:
Human   105 ------------GFK--TMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANA 155

  Fly    98 -------LW-----------GADHDFTLEEVLSEIAFFRGESYHTVHECSGEEVTAS-------- 136
                   :|           ...|...|:        ..|::::.:...|..|...:
Human   156 TRNLNFSIWNHTPLVLIDERNPHHPMVLD--------LFGDNHNGLTSSSASEKICNAHGCKMAM 212

  Fly   137 ---------CFYSNF------------------------------SYYAELVRSSCVDSISNCEW 162
                     |.:.||                              ||..|.:..:|:.....|.:
Human   213 RLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNY 277

  Fly   163 NNKPFECCKYFHRMETELGICYAINSMQAGKPKMPKLNMYSNRGSGPG---ALKMELHTEATVFI 224
            .|  |....|.|     .|.||..|.....| .:|..|        ||   .||:       :..
Human   278 RN--FTSIFYPH-----YGNCYIFNWGMTEK-ALPSAN--------PGTEFGLKL-------ILD 319

  Fly   225 LGTEE-VPTLVTPKTDFLVVGPYIS--FVRYISKRDIENDEEI-----RQTSVH------QR--- 272
            :|.|: ||.|.:.....|::....|  |:|         ||.|     .:||:.      ||
Human   320 IGQEDYVPFLASTAGVRLMLHEQRSYPFIR---------DEGIYAMSGTETSIGVLVDKLQRMGE 375

  Fly   273 ---NCRFADENI------LDVHKFYSYSACTVQCRKDRQMELCNCSSHLSP-----------NSP 317
               .|......:      .|.:..||..||...|.:|..:..|||..:|.|           :.|
Human   376 PYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFP 440

  Fly   318 DWQLCNMEGLECLNRNYEDLSVIIAKWSKLRGRKGLVCDCLPSCTEVD----------------- 365
            ||..|           |.||.:.:|:      |:..:..|..||.:..
Human   441 DWAHC-----------YSDLQMSVAQ------RETCIGMCKESCNDTQYKMTISMADWPSEASED 488

  Fly   366 -----ITTVYDSKENMAGSQNAISRIEVGLIELPTERYKRNLVRGKLDLVVSIGGTTGLFVGASL 425
                 ::...|...|:..|:..|.::.:...|......:.:.....:.|:.::||..|.::|.|:
Human   489 WIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSV 553

  Fly   426 LSFVEI------FYYITI 437
            |..:|.      |.:|||
Human   554 LCLIEFGEIIIDFVWITI 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	111/591 (19%)
SCNN1B	XP_016879014.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820