Protein Alignment ppk13 and asic4b

DIOPT Version :10

• Sequence 1: NP_001014495.1
• Gene: ppk13 / 3346226
• FlyBaseID: FBgn0053508
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_999951.1
• Gene: asic4b / 407667
• ZFINID: ZDB-GENE-040513-6
• Length: 558
• Species: Danio rerio
• Alignment Length: 511
• Identity: 119/511 - (23%)
• Similarity: 183/511 - (35%)
• Gaps: 130/511 - (25%)

  Fly     7 IEEYLKNSTLHG-ARFIVDKDASWIERIFWVICLV---------ASWYASWLLIKASLSAFENNA 61
            :..:..:|:||| ||.:...:.....:..|.:.|:         |:|.|:..|.:..|:|..
Zfish    44 LASFASSSSLHGLARALGTSERLGFRQTLWGLALLVSLGLFLYQATWSAATYLERPHLAALR--- 105

  Fly    62 ISFVVESSFRDWNTNFPAIIVCESKNMDRIQEVAEQLWGADHDFTLEEVLSEIAFFRG-----ES 121
                 |.:.|:  ..||||.:|   |::|.:..|  |..||        :..:|...|     ..
Zfish   106 -----EETRRE--LTFPAITLC---NVNRFRFSA--LTDAD--------IYHLANLTGLPPKSRK 150

  Fly   122 YHTVHECSGEEVTASCFYSNFSYYAELVRSSCVDSISNCEWNNKPFECCKYFHRMETELGICYAI 186
            .|...|...........:....:..|.:..||..|..||...:        |..:.|..|.||..
Zfish   151 GHRPSELQYPPPNMLDIFQRTGHQLEDMLKSCNFSGQNCSSED--------FSVVYTRYGKCYTF 207

  Fly   187 NSMQAGKPKMPKLNMYSNRGSGPGALKMELHTEATVFILGTEEVPTLVTPKTDFLVVG------- 244
            |    |....||.......|:|   |:|.|.      |...|.:|.........|..|
Zfish   208 N----GNKTSPKRVRQGGTGNG---LEMMLD------IQQDEYLPIWRETNETTLEAGIRVQIHS 259

  Fly   245 ----PYI---------SFVRYISKRDIENDEEIRQTSVHQ--RNCRFADENILDVHKFYSYSACT 294
                |||         .|..::|      .:|.|.|.:.|  .|||.:.|.::..:..||.|||.
Zfish   260 QNEPPYIHQLGFGVSPGFQTFVS------CQEQRLTYLPQPWGNCRASSEPVIPGYDTYSVSACR 318

  Fly   295 VQCRKDRQMELCNCSSHLSPNSPDWQLCNMEGLECLNRNYEDLSVIIAKWSKLRGRKGLVCDCLP 359
            :.|...:....|||.....|...|  :|....::|:::       .:|...|..|..   |.|..
Zfish   319 LHCESTQVQRECNCRMVHMPGDAD--ICAPSKIKCVDK-------ALASLQKSTGDS---CPCET 371

  Fly   360 SCTEVDITTVYDSKENMA-----GSQNAISR---------------IEVGLIELPTERYKRNLVR 404
            .|.    .|.|..:.:|.     ||...:||               :::....|..|..::....
Zfish   372 PCN----LTRYGKELSMVKIPSRGSARYLSRKYQKSEEYIRDNFLILDIFFEALNYETIEQKKAY 432

  Fly   405 GKLDLVVSIGGTTGLFVGASLLSFVEIFYYITIRPYTTYINEKRRLKRLIIPKRFQ 460
            ....|:..|||..|||:|||:|:.:||..||       |...|.::|:|:.||:.|
Zfish   433 DIAGLLGDIGGQMGLFIGASILTILEILDYI-------YEVAKNKIKQLLKPKKSQ 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk13	NP_001014495.1	ASC	10..434	CDD:459966	110/480 (23%)
asic4b	NP_999951.1	ENaC	54..497	CDD:273304	117/501 (23%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:P78348	450..452		1/1 (100%)