DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk13 and ppk

DIOPT Version :9

Sequence 1:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_477232.1	Gene:	ppk / 34843	FlyBaseID:	FBgn0020258	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	114/536 - (21%)
Similarity:	200/536 - (37%)	Gaps:	131/536 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EYLKNSTLHGARFIVDKDASWIERIFWVI--CLVASWYASWLLIKASLSAFENNAISFVVESSFR 71
            ||.|::|:||.|:|.:......|:::|:.  | ::.::|..|:....|...|:..|....|:...
  Fly    68 EYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTC-ISVYFAVSLIWDTYLKWQESPVILGFDETLVP 131

  Fly    72 DWNTNFPAIIVCESKNMDR----IQEVAEQLWG--------ADHDFTLEEVLSEIAFFRGESYHT 124
            .....||.|.:|....|:|    ...|:.|||.        :|.|   :|.|:.:|.       .
  Fly   132 VHKIPFPTITICPEIKMERNVFDYTNVSRQLWEEYKQNGNISDLD---DEDLARMAV-------A 186

  Fly   125 VHECSGEEVTASCFYSNFSYYAELVRSSCVD--------SISN------CEWNNKPFECCKYFHR 175
            :|.|..|.|      ..|:.....:....||        |||.      |:||.:.:.|.|.|..
  Fly   187 MHICDSEVV------QRFTPLLSQLNPPNVDVTQTLIDLSISKNETGPFCKWNGRFYFCDKIFDF 245

  Fly   176 METELGICYAINSMQ-----------------------------------------------AGK 193
            :.|:.||||..|.::                                               .|:
  Fly   246 VATDEGICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPWNNITGNWSLDTGFVDQGQ 310

  Fly   194 PKMPKLNMYSNRGSGPGALKMELHTE-----------ATVFILGTEEVPT-----LVTPKTDFLV 242
            ...|:..::|:..:|..|....|...           ..||:...|.||.     ::.|..|.::
  Fly   311 NAYPQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYKVFLNSPESVPLTTGNYILVPHGDEVL 375

  Fly   243 VGPYISFVRYISKRDIENDEEIRQTSVHQRNCRFADENILDVHKFYSYSACTVQCRKDRQMELCN 307
            |....::|        .:.:.:.:.:..:|.|.|.||..|...:.||.|.|..:|..:..:..|.
  Fly   376 VSVLPAYV--------VSTDNLHEITPEKRQCLFDDERSLRFFRSYSQSNCQTECLANYTVSKCG 432

  Fly   308 CSSHLSPNSPDWQLCNMEGLECLNRNYEDLSVIIAKWSKLRG---RKGLVCDCLPSCTEVDIT-- 367
            |:....|......:|.::.:.|.....::|..::...:..:.   ...:.|:|:|:||.::..
  Fly   433 CAKFWMPKPLGTPVCGLKDINCYTSAQDELYTLMQNQTMAKSIDESVDITCNCMPACTSLEYNFE 497

  Fly   368 ----------TVYDSKENMAGSQNAISRIEVGLIELPTERYKRNLVRGKLDLVVSIGGTTGLFVG 422
                      |:...:|....:....||:.|...|......||.::.|...|:.:.||..|||:|
  Fly   498 ISRAKYDVAKTIRAFREEYEHTDAIGSRLSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMG 562

  Fly   423 ASLLSFVEIFYYITIR 438
            .|.|||:|:.|:..:|
  Fly   563 ISCLSFLELIYFFCMR 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	111/529 (21%)
ppk	NP_477232.1	ASC	69..574	CDD:279230	111/529 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	5	4.920