DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk13 and ppk14

DIOPT Version :9

Sequence 1:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_609017.2	Gene:	ppk14 / 33887	FlyBaseID:	FBgn0031803	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	103/491 - (20%)
Similarity:	187/491 - (38%)	Gaps:	72/491 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VIEEYLKNSTLHGARFIVDKDASWIERIFWVICLVAS----WYASWLLIKASLSAFENNAISFVV 66
            :|:.|:..|.:||...:.........|:.|.:.|:.:    ::.|:||    ...:.|.....:|
  Fly    41 LIDSYISRSHIHGLYLLFLPSMRRRMRVLWALALICACTVLFHVSYLL----GDRYHNKQFQTIV 101

  Fly    67 ESSFRD-WNTNFPAIIVCESK--NMDRIQEVAEQLWG--ADHDFTLEEVLSEIAFFRGESYHTVH 126
            ..:... .:..||.:|:|...  |..|:.|: :.|:.  ...|...:.:|:....|....::...
  Fly   102 AHAHASIHHIAFPVVIICNKNRLNWSRLPEI-KSLYNITPSQDELFDRILTAYDGFSFHKFNAFD 165

  Fly   127 ECSGEEVTASCFYSNFSYYAELVRSSCVDSISNCEWNNKPFECCKYFHRMETELGICYAINSMQA 191
            ...||.:. ...:.||:.....:...|.:.:.:|.|.....:|||.|......||.|.|.|.::.
  Fly   166 SLLGESLD-ELNHLNFTEIVIQMSWRCDEILRDCHWQTASRDCCKLFRPRRLPLGYCLAFNELEK 229

  Fly   192 GKPKMPKLN------------MYSNRGSGPGALKMELHTEATVFILGTEEVPTLVTPKTDFLVVG 244
            .:.....:|            .::...||.....:.:...:..|....|.||   ..:|:..|..
  Fly   230 RRGTETGINTGLLLRLLLREGQHAPGNSGLKGFWLTVVESSVWFGFPIEVVP---HSRTNVAVTA 291

  Fly   245 PYISFVRYISKRDIENDEEIRQTSVHQRNC--RFADEN----ILDVHKFYSYSACTVQCRKDRQM 303
            .|..|           ||.........|:|  .:.:|:    .|:..| |....|..:|::...:
  Fly   292 VYHYF-----------DESTLSLPSSWRHCVMDYEEESEHFRTLEGQK-YMLENCQAECQQRYLL 344

  Fly   304 ELCNCSSHLSPNSPDWQLCNMEGLECLN------RNYE---DLSVIIAKWSKLRGRKGLVCDCLP 359
            ..|||:..|.....::..|.::.|.||.      :|:|   :...:      .|...||||:||.
  Fly   345 RYCNCTVDLFYPPSNYPACRLKDLPCLAAHNHLLQNFEQPGEHPYV------HREESGLVCECLH 403

  Fly   360 SCTEVDITTVYDSKENMAGSQNAISRIEVGLIELPTER-----YKRNLVRGKLDLVVSIGGTTGL 419
            :|..:.:.|...........|...|.||...:.:..::     ||.||:...:||:||.||...|
  Fly   404 NCKSLTLLTDMRKSVQQPWLQPNSSAIESMWLNVYFKKPSMLVYKTNLIYTWVDLIVSFGGICQL 468

  Fly   420 FVGASLLSFVEIFYYITIRP----YTTYINEKRRLK 451
            .:|.|::|.:|..::...:.    :..:.||.|..|
  Fly   469 CLGCSIISLIEFVFFALYKVPQLYWERFSNEHRSNK 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	98/464 (21%)
ppk14	NP_609017.2	ASC	45..483	CDD:279230	98/464 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020