Protein Alignment ppk13 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001014495.1
• Gene: ppk13 / 3346226
• FlyBaseID: FBgn0053508
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 111/613 - (18%)
• Similarity: 183/613 - (29%)
• Gaps: 238/613 - (38%)

  Fly     3 FSRVIEEYLKNSTLHGARFIV----DKDASWIERIFWVICLVA-SW------YASWLLIKASLSA 56
            :..::..|..|:..||.:.|:    .|.|.|........|||. .|      |.||
  Rat    22 YKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSW--------- 77

  Fly    57 FENNAISFVVESSFRDWNTNFPAIIVCES------------KNMDRIQEVAEQ------------ 97
                .:|..:...|:  ..||||:.||.|            |::.::.|....
  Rat    78 ----EVSVSLSMGFK--TMNFPAVTVCNSSPFQYSKVKHLLKDLYKLMEAVLDKILAPKSSHTNT 136

  Fly    98 -------LW-----------GADHDFTLEEVLSEIAFFRGESYHTVHECSGEEVTAS-------- 136
                   :|           ..||...|.        ..|:|:::.:...|....|.
  Rat   137 TSTLNFTIWNHTPLVLIDERNPDHPVVLN--------LFGDSHNSSNPAPGSTCNAQGCKVAMRL 193

  Fly   137 -------CFYSNFSYYAELVRSSCVDSISN-----------------------CEWNNKPFECCK 171
                   |.:.||:...:.|....:...:|                       |.:..:|   |.
  Rat   194 CSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEP---CS 255

  Fly   172 YFHRMET-----ELGICYAINSMQAGKPKMPKLNMYSNRG-----------------SGPGALKM 214
              ||..|     :.|.||..|.....| .:|..|..:..|                 |..|| ::
  Rat   256 --HRNFTPIFYPDYGNCYIFNWGMTEK-ALPSANPGTEFGLKLILDIGQEDYVPFLASTAGA-RL 316

  Fly   215 ELHTEATVFILGTEEVPTLVTPKTDFLVV--------GPYISFVRYISKRDIENDEEIRQTSVHQ 271
            .||.:.|...:..|.:..:...:|...|:        .||.......|...|:|
  Rat   317 MLHEQRTYPFIREEGIYAMAGTETSIGVLLDKLQGKGEPYSPCTMNGSDVAIQN----------- 370

  Fly   272 RNCRFADENILDVHKFYSYSACTVQCRKDRQMELCNCSSHLSP-----------NSPDWQLC--- 322
               .::|.|..     ||..||...|.:|..:..|:|..:|.|           :.|||..|
  Rat   371 ---LYSDYNTT-----YSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLS 427

  Fly   323 ------------NMEGLECLNRNYEDLSVIIAKWSKLRGRKGLVCDCLPSCTEVD-----ITTVY 370
                        :|....|.:..|: :::.:|.|              ||....|     ::...
  Rat   428 LQMSVVQRETCLSMCKESCNDTQYK-MTISMADW--------------PSEASEDWILHVLSQER 477

  Fly   371 DSKENMAGSQNAISRIEVGLIELPTERYKRNLVRGKLDLVVSIGGTTGLFVGASLLSFVEI---- 431
            |...|:..|:..|.::.:...|......:.:.....:.|:.::||..|.::|.|:|..:|.
  Rat   478 DQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEII 542

  Fly   432 --FYYITI----------------RPYT 441
              |.:||:                ||||
  Rat   543 IDFIWITVIKLVASCKGLRRRRPQRPYT 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	105/581 (18%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	111/613 (18%)
		deg-1	29..538	CDD:273309	103/572 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820