DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk13 and mec-4

DIOPT Version :9

Sequence 1:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_510712.2	Gene:	mec-4 / 181728	WormBaseID:	WBGene00003168	Length:	768	Species:	Caenorhabditis elegans

Alignment Length:	342	Identity:	63/342 - (18%)
Similarity:	116/342 - (33%)	Gaps:	59/342 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 ISNCEWNNKPFEC-CKYFHRMETELGICYAINSMQAGKPKMPKLNMYSNRGSGPGALKMELHTEA 220
            :..|.:|.|..:. ..:...::...|.|:..|..:.       :|:.|.|......|:|.::..|
Worm   447 VHKCSFNGKACDIEADFLTHIDPAFGSCFTFNHNRT-------VNLTSIRAGPMYGLRMLVYVNA 504

  Fly   221 TVFILGTEEVPTLVT--PKTDFLVVGPYISFVRYISKRDIENDEEIRQTSVHQRNCRFAD----- 278
            :.::..||.....:|  .|.||    |:.....|.:.....:...:|...:.:....:.|
Worm   505 SDYMPTTEATGVRLTIHDKEDF----PFPDTFGYSAPTGYVSSFGLRLRKMSRLPAPYGDCVPDG 565

  Fly   279 --ENILDVHKFYSYSACTVQCRKDRQMELCNCSSHLSPNSPDWQLCNME---GLECLNRNYEDLS 338
              .:.:..:..||...|...|.:...::.|.|.....|...:.:.|:..   ..:||:....||.
Worm   566 KTSDYIYSNYEYSVEGCYRSCFQQLVLKECRCGDPRFPVPENARHCDAADPIARKCLDARMNDLG 630

  Fly   339 VIIAKWSKLRGRKGLVCDCLPSCTEVDITTVYD-------SKENMAGSQNAI------------S 384
            .:...:.         |.|...|.:...:..|.       |.:...||.|..            :
Worm   631 GLHGSFR---------CRCQQPCRQSIYSVTYSPAKWPSLSLQIQLGSCNGTAVECNKHYKENGA 686

  Fly   385 RIEVGLIELPTERYKRNLVRGKLDLVVSIGGTTGLFVGASLLS-------FVEIFYYITIRPYTT 442
            .:||...:|..|....:...|.::|:...||..||:.|.|.|:       |:|..|......|:.
Worm   687 MVEVFYEQLNFEMLTESEAYGFVNLLADFGGQLGLWCGISFLTCCEFVFLFLETAYMSAEHNYSL 751

  Fly   443 YINEKRRLKRLIIPKRF 459
            |..:|....:.|....|
Worm   752 YKKKKAEKAKKIASGSF 768

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	57/315 (18%)
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	55/308 (18%)
		ASC	87..>172	CDD:279230
		ASC	<428..739	CDD:295594	56/311 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820