DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk13 and del-10

DIOPT Version :9

Sequence 1:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_495302.3	Gene:	del-10 / 174069	WormBaseID:	WBGene00020897	Length:	1069	Species:	Caenorhabditis elegans

Alignment Length:	480	Identity:	96/480 - (20%)
Similarity:	176/480 - (36%)	Gaps:	138/480 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ASWIERIFWVICLVASWYASWLLIK--ASLSAFENNAISFVVESSFRDWNTNFPAIIVCESKNM- 88
            ||.:.|..|  |::...:...:|::  :.:..:.:..::..:|:.:.. ..:||.:.:|.:...
Worm    89 ASPVTRGLW--CMIIIAFVILVLVQCYSQIKLYISEPVATNIEAEYPS-KISFPTVAICNNNQFR 150

  Fly    89 -----------DRIQEVAEQLWGADHDFTLEEVLSEIAFFRGESYHTVHECSGEEVTASCFYSNF 142
                       .|.:.::..|....||  :|.|           :.||...|. ::.|..|..:.
Worm   151 LTYLTGGRIMNRRSKSISGSLLSTGHD--VESV-----------FDTVLRKSW-DMDAVKFLRSA 201

  Fly   143 SYYAELVRSSCVDSISNCEWNNKPFECCKY--FHRMETELGICYAINSMQAGKPKMPKLNMYSNR 205
            :::...:       |..|.|.|.  ..||.  |..:.|..|:|:|||:    .|..|    |...
Worm   202 AHWKSRM-------ILGCTWPNG--TSCKLSDFKAVWTTTGLCWAINT----DPHNP----YEVT 249

  Fly   206 GSGPG-ALKMELHTEA-------------------TVFILGTEEVPTL----VTPKTDFLVVGPY 246
            |||.| .|::.|:.|:                   .:.|....::|..    |...:.:.:..|:
Worm   250 GSGEGHGLRLLLNVESYERVDACTKHFRTKTLPGLKILIYNQTDIPDSSMNGVNVPSGYSMDIPF 314

  Fly   247 -------ISFVRYISKRDIENDEEIRQTSVHQRNCRFADENILDVHKFYSYSACTVQCRKDRQME 304
                   ::.|..|.    ||||:| :.|....|    .|||         ..||::........
Worm   315 KMQHRSKLTGVHCIE----ENDEQI-EASTDFNN----PENI---------RTCTLRRYMTEVEN 361

  Fly   305 LCNCSSH--LSPNSPDWQL--CNMEG-LECLNRNYEDLSVIIAKWSKLRGRKGLVCDCLPSCTEV 364
            .|:|:..  .:.||.|.::  ||::. ..|..:..:          ::| .:|....|||.|..:
Worm   362 SCHCTLRRAYTSNSTDVKMKACNVDQYFGCAQKAMQ----------RIR-EEGTASTCLPPCKSI 415

  Fly   365 DITTVYDSKENMAGSQNAISRIEVGLIELPTERYKRNLVRGKLDLVVSIGGTTGLFVGASLLSFV 429
            |.|...|....   .||.:.    .|||...|..:.::.:.:||..||....:    |....|..
Worm   416 DYTAWQDMNRL---PQNLMP----ALIEEQEEDDEDDVEQEELDENVSFSTVS----GGETFSCE 469

  Fly   430 EIFYYITIRPYTTYINEKR--RLKR 452
            :          :.|:::|:  |:||
Worm   470 D----------SAYLDDKQVMRIKR 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	91/458 (20%)
del-10	NP_495302.3	ASC	83..>419	CDD:279230	77/392 (20%)
del-10	NP_495302.3	ASC	<789..849	CDD:279230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820