DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33509 and CG6834

DIOPT Version :9

Sequence 1:	NP_001014494.1	Gene:	CG33509 / 3346225	FlyBaseID:	FBgn0053509	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster

Alignment Length:	407	Identity:	97/407 - (23%)
Similarity:	161/407 - (39%)	Gaps:	76/407 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ECQKILENAQESAVR------VKLLDYHLVRDLSAIGYLGDYYALTLRYCHEEEEIIREIELFVK 64
            |..||:..:..||.:      .|||...:...|.      |:.:.|..|             .:|
  Fly   514 EFDKIVGGSWSSATKPGDNFASKLLKIDIETQLK------DHTSKTFSY-------------ILK 559

  Fly    65 AMPQQSAE-LSKESIFQKESWLYDTLIKKLQAL-----SNVKWSPNCVYSRK----DLMVLENIK 119
            ..|:.:.: .:..::|.||..:|...:...:.|     ..|.::.|.....|    :.:::||::
  Fly   560 VQPKSTPDNFTDVNMFPKEMEMYQKYVPAFEQLYKDAGLTVTFTANSFVLNKAVKEEYLLMENLQ 624

  Fly   120 LKGFTSAGSAE-LNEVFVKPLIKSIAAFHSASLVYEHQTKTNIGH--TYGDNL-LEITVDSEIAW 180
            .|||..|...: ||....|..:|.:|.:|:||:.|:   :.|..:  .|.|.: :|.|.|   .:
  Fly   625 TKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYK---ELNGAYPPLYNDGIYIEQTRD---VF 683

  Fly   181 FTTGLSAVLAVVRSLAKYQGNREQSFIGDKLMGIMET----IYEQAAPSKKYRNVLCHRDIWAGN 241
            .....||..|.:|....::|..|..   .||..|::.    :.|.|..:::..|||.|.|.|..|
  Fly   684 HNMFASAKEAYIRIFGTFEGADEYL---PKLEWIIDNHVDQVLEDAKINEQAFNVLNHGDAWINN 745

  Fly   242 IFFPPENSG---PALLIDFQTCRYAPPASDLNFCLYMNLSSSKRKQMEKQGID----LYHTYLLQ 299
            |.|..:..|   ...|:|.|..:|..||.|    ||..|.||....::....|    .||..|::
  Fly   746 IMFQYDAEGRLKETYLLDHQNAKYGNPAQD----LYYFLISSAELDIKVDEFDNLIRFYHENLVE 806

  Fly   300 NLSDLGLEELVISKSELLESYEEFRLFGVVYRAVAATVVKVPTDFITND-------FKYVDRSKV 357
            :...|.....|.|.|||.....|...|.|      .||:...|..:|::       |.....|:.
  Fly   807 HTKLLKYNGFVPSLSELHAILIEHPAFAV------GTVISTLTVCLTDEGFNPELFFVETPESEA 865

  Fly   358 ILSYMKTNPEFATYMEE 374
            ..:.:..|..:..::|:
  Fly   866 FRTKLLGNERYKAHVEK 882

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33509	NP_001014494.1	PKc_like	63..305	CDD:304357	68/266 (26%)
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	76/315 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459710
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840