DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-37Da and Clec4e

DIOPT Version :9

Sequence 1:	NP_001014489.1	Gene:	lectin-37Da / 3346222	FlyBaseID:	FBgn0053532	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_064332.1	Gene:	Clec4e / 56619	MGIID:	1861232	Length:	214	Species:	Mus musculus

Alignment Length:	157	Identity:	34/157 - (21%)
Similarity:	59/157 - (37%)	Gaps:	17/157 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 YDKYTTHIQNGNPYNLTVDMTPFIKINESYYVFGQTKVNWYVAYENCRRLQSELVTFETAEEFDA 85
            |.:.:..::|..|.|       :.....|.|.|..|.:.|..:.:||..:.:.||..:|.||.:.
Mouse    69 YSEASGSVKNCCPLN-------WKHYQSSCYFFSTTTLTWSSSLKNCSDMGAHLVVIDTQEEQEF 126

  Fly    86 IAAFLNARGDRSEHWTSGNDLGKTGTHYWFSNAQLV-TIKRWAPKQPDNAGGREHCIHLGYIYGY 149
            :   ...:..|.|.:....|....|...|..:.... ::..|...:|:|....|.|..:.  ...
Mouse   127 L---FRTKPKRKEFYIGLTDQVVEGQWQWVDDTPFTESLSFWDAGEPNNIVLVEDCATIR--DSS 186

  Fly   150 STEFQLNDRPCHNHASSLFKYICEAPK 176
            ::....||.||...    ..:|||.|:
Mouse   187 NSRKNWNDIPCFYS----MPWICEMPE 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-37Da	NP_001014489.1	CLECT	49..173	CDD:153057	27/124 (22%)
Clec4e	NP_064332.1	CLECT_DC-SIGN_like	80..207	CDD:153060	30/142 (21%)
Clec4e	NP_064332.1	Confers specificity for glucose/mannose-type carbohydrates. /evidence=ECO:0000250\|UniProtKB:Q9ULY5	169..171		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	59	1.000	Inparanoid score	I5406
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.150