DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-37Da and ASGR1

DIOPT Version :9

Sequence 1:	NP_001014489.1	Gene:	lectin-37Da / 3346222	FlyBaseID:	FBgn0053532	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_001662.1	Gene:	ASGR1 / 432	HGNCID:	742	Length:	291	Species:	Homo sapiens

Alignment Length:	149	Identity:	36/149 - (24%)
Similarity:	56/149 - (37%)	Gaps:	22/149 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GNPYNLTVDMTPFIKINESYYVFGQTKVNWYVAYENCRRLQSELVTFETAEEFDAIAAFLNARGD 95
            ||....|.....:::...|.|.|.::...|..|...||...:.||...:.||    ..|:.....
Human   146 GNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEE----QKFVQHHIG 206

  Fly    96 RSEHWTSGNDLGKTGTHYWFSNAQLVT-IKRWAPKQPDN-----AGGREHCIHLGYIYGYSTEFQ 154
            ....|...:|  :.|...|.......| .|.|.|:|||:     .||.|.|.|      ::.:.:
Human   207 PVNTWMGLHD--QNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAH------FTDDGR 263

  Fly   155 LNDRPCHNHASSLFKYICE 173
            .||..|...    ::::||
Human   264 WNDDVCQRP----YRWVCE 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-37Da	NP_001014489.1	CLECT	49..173	CDD:153057	31/129 (24%)
ASGR1	NP_001662.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		Endocytosis signal. /evidence=ECO:0000255	5..8
		Lectin_N	17..144	CDD:309178
		CLECT_DC-SIGN_like	154..279	CDD:153060	33/141 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910