Protein Alignment Ddr and ddr2l

DIOPT Version :10

• Sequence 1: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Sequence 2: XP_073808071.1
• Gene: ddr2l / 565333
• ZFINID: ZDB-GENE-041210-162
• Length: 873
• Species: Danio rerio
• Alignment Length: 1004
• Identity: 333/1004 - (33%)
• Similarity: 471/1004 - (46%)
• Gaps: 213/1004 - (21%)

  Fly   106 CKQALGMESGAIADFQITASSA-HDMGNVGPQHARLKIDNNGGAWCPKHMVSRGLTEYLQVDLLG 169
            |:..||||.|.|.:..|||||. :|  :.|||:|||..:...||||....:.....:|||:||..
Zfish    23 CRYPLGMEDGRIKNDDITASSQWYD--STGPQYARLNREEGEGAWCAAGQLQPSDVQYLQIDLRQ 85

  Fly   170 VHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQP 234
            :..::.:.||||:.:..|.|:...|.:||.|.| .:||.||:..|.|::.||:|||..|...|.|
Zfish    86 LIFLTVVATQGRYARNSGIEFARKYRLEYSRDG-HRWISWRNRFGNEIIMGNVNTYDTVVRDLHP 149

  Fly   235 SVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSYSIPKG---MQRGMDI-DLSDKTYDGYEE 295
            .:....:||.|.:....|||:|.|:.||||::|:::||.|:|   |..|..| .|:|.||||..|
Zfish   150 PIITRFLRLIPVTDAVHTVCMRVELFGCAWQDGLMAYSSPEGQIMMAPGFPITSLNDSTYDGPLE 214

  Fly   296 GDHYVNGLGQLVDGQRGKDNF-RADINGLGKGYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVII 359
            ......|||||.||..|.|:| .:....|..||:::|||||.|....||:.|:|:..||.:::.:
Zfish   215 RRKLSGGLGQLADGVVGLDDFVESRQYRLWPGYDYVGWRNDGLGPGYVEMEFQFDRQRNFTSMKV 279

  Fly   360 HTNNMFSKDVQVFVHAKVFFSIGGRH----FSGEPVQFSYMPDLVLDHARDVTIKLHHRLGRYVQ 420
            |:|||||..|::|......|.:   |    :..|||:|..:.|.....||.|||.|.||....::
Zfish   280 HSNNMFSMGVKIFSSVSCVFKL---HLISEWESEPVEFHTVIDDRNPSARYVTIPLKHRSATALR 341

  Fly   421 LHLYFAARWMMISEITFISAPVVGNFTDELANGEKQSVTSEYPLQRDEV-----GRAISSGGERS 480
            ...|||..|||.|||:|                  ||||...|.::..|     ..|.|...|.:
Zfish   342 CRFYFADTWMMFSEISF------------------QSVTIVLPTKKPPVLTPPSYEANSEIPETT 388

  Fly   481 QHTTQVISPKPIDHQEPETSFVGVIITVLGTIIMLLVAFILLIVARNKHVRSRENGLDAFQHNFS 545
            |.|....:|....  .||.....::|..|.|||:|||..|.||
Zfish   389 QKTEDWTTPTKTG--SPEEGNTSILIGCLVTIILLLVVIIFLI---------------------- 429

  Fly   546 PDTLNGNGVLKVVTTMDDNESSIDKNSLYHEPFNANMYTSAASACPMNDLQRQHVSPDYTDVPDI 610
                                                                            :
Zfish   430 ----------------------------------------------------------------L 430

  Fly   611 VCQDYAVPHMQQLLPNAPPCGSGCGTGTGTGPGRGSSPEFVVATGKVTASARNSLNAATLPLPSP 675
            .||     ::.::|..||               |....|.|        :.|.|.::.|:.|.:|
Zfish   431 WCQ-----YVCKVLEKAP---------------RRILEEEV--------AVRLSSSSDTIILQTP 467

  Fly   676 PVP------PPLEKYYAATPVSSKPMPV---APPGSQS------SGSLSSSTTAATTPTSGVVGV 725
            |||      ||.|:.:...|....|..:   .|..|||      ||..:.......||......
Zfish   468 PVPPRVSIDPPYERIFLLDPQYQDPAALRNKLPELSQSAETSACSGGYAEPDVTLCTPHQSFQS- 531

  Fly   726 GKPHHYNLDM-------SANFADI------NEERANCQVQEFPRQSLVIVEKLGSGVFGELHLCE 777
            ..||:...|:       .:|...:      :..|.:..|.|||||.|:..||||.|.|||:||||
Zfish   532 SAPHYAETDIISLQGVTGSNMYSVPALTVDSLTRKDISVAEFPRQRLLFREKLGEGQFGEVHLCE 596

  Fly   778 TNVL---------------NATLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLR 827
            ...|               ...||||..||..|..:.|.:|..:.|.:::|::||:.:|:..|:.
Zfish   597 AEGLAEFLGEGAPLPEQDGRPVLVAVKQLRADATSNARNDFLKEIKIMSRLNNPNIIQLLCVCVS 661

  Fly   828 DEPICIVQDYSHCLGDLNQFLQEHVAETSGLMAKK--SLSFGCLVYIATQIASGMKHLEQMNFVH 890
            .:|:|:|.:|.. .||||.||.:...|::...|..  |:|...|::::.||:||||:|..:||||
Zfish   662 SDPLCMVTEYME-NGDLNMFLSQREIESTLTHANNIPSVSIADLLHMSVQISSGMKYLASLNFVH 725

  Fly   891 RDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAWESVLLGKFTT 955
            ||||||:|::...|.:|:...|  ::|:.|:|||.:::|     ...:|||||||||:|||||||
Zfish   726 RDLATRNCLLDRHLTIKISDFG--MSRNLYSSDYYRIQG-----RAVLPIRWMAWESILLGKFTT 783

  Fly   956 KSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCEC 1020
            .||||:|.|.||||.|..:||||..|||:.||||.|..:|:......|..||.||..::.||..|
Zfish   784 ASDVWAFGVTLWEIFTLCKEQPYSLLSDEQVIENTGEFFRNQGRQIFLSAPPLCPSSLFKLMMRC 848

  Fly  1021 WQRDESSRPSFREIHLYLQRKNLGFKPQT 1049
            |.||.:.||||.::|..|:.    |.|.:
Zfish   849 WSRDITDRPSFNKLHQALRT----FAPHS 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddr	NP_001014474.3	FA58C	109..261	CDD:238014	60/152 (39%)
		PTKc_DDR	753..1040	CDD:270644	133/303 (44%)
ddr2l	XP_073808071.1	None