Protein Alignment Ddr and Ddr

DIOPT Version :10

• Sequence 1: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Sequence 2: XP_061511090.1
• Gene: Ddr / 4578049
• VectorBaseID: AGAMI1_011800
• Length: 957
• Species: Anopheles gambiae
• Alignment Length: 1006
• Identity: 625/1006 - (62%)
• Similarity: 752/1006 - (74%)
• Gaps: 93/1006 - (9%)

  Fly    59 NSKTLCW--LTLTLILLANRF-GMGTAVGTPETPAAVGSNGLLAEMPIGTCKQALGMESGAIADF 120
            |:.|..|  ..|.|:|:...| |:.|                   :.:..||..|||||.||.|.
Mosquito    12 NACTTWWTRFALVLLLMQQTFHGVQT-------------------LDLDKCKNPLGMESFAINDS 57

  Fly   121 QITASSAHDMGNVGPQHARLKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKG 185
            |||||||||:|||||||||||:|||||||||||||||||.||||:|||.:|:::||:||||||||
Mosquito    58 QITASSAHDIGNVGPQHARLKVDNNGGAWCPKHMVSRGLKEYLQIDLLKMHVITAIKTQGRFGKG 122

  Fly   186 QGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYD 250
            ||:||||||.:||||||..||.||::.:..|:|.||||||||||..|||.:||||:|:|||||||
Mosquito   123 QGREYTEAYALEYWRPGFTKWKRWKNTRDNEILSGNINTYSEVEQALQPIIFASKIRIYPYSQYD 187

  Fly   251 RTVCLRAEIVGCAWEEGIVSYSIPKGMQRGMDIDLSDKTYDGYEEGDHYVNGLGQLVDGQRGKDN 315
            |||||||||:||.||||::|||||||:.||:::||||:||||..|||..|:|||||||||:|.||
Mosquito   188 RTVCLRAEIIGCEWEEGLISYSIPKGVIRGVEVDLSDRTYDGEGEGDRLVHGLGQLVDGQKGADN 252

  Fly   316 FRADINGLGKGYEWIGWRNDTL--LGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVF 378
            ||.||:|.||||:|:|||||:|  .|:|||::|||::|||.|::::|||||||||||||||||||
Mosquito   253 FRIDIHGFGKGYDWVGWRNDSLGWAGKPVEMVFEFDSVRNFSSMVLHTNNMFSKDVQVFVHAKVF 317

  Fly   379 FSIGGRHFSGEPVQFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPVV 443
            |||||:||:|||||||||||.|:::|||||||||||:|||||:|||||.||:|:|||:|.||||.
Mosquito   318 FSIGGQHFTGEPVQFSYMPDTVMENARDVTIKLHHRVGRYVQIHLYFALRWIMLSEISFNSAPVT 382

  Fly   444 GNFTDELANGE--KQSVTSEYPLQRDEVGRAISSGGERSQHTTQVISPKPIDHQEPETSFVGVII 506
            |||:||..||.  .|..:.||||||||.|..|.:.|||: |.||:||||||| ||||..||||:|
Mosquito   383 GNFSDEEVNGNSISQENSIEYPLQRDESGINIVNKGERN-HVTQIISPKPID-QEPEPHFVGVVI 445

  Fly   507 TVLGTIIMLLVAFILLIVARNKHVRSRENGLDAFQHNFSPDT------LNGNGVLKVVTTMDDNE 565
            ..|.|||:||:..|:.|||:||..|:.. .|||.|||...|:      ||.|  .||  ::||||
Mosquito   446 AALTTIILLLIVIIMFIVAKNKRTRTAA-VLDALQHNLHTDSLGIDKRLNSN--FKV--SIDDNE 505

  Fly   566 SSIDKNSLYHEPFNANMYTSAASACPMNDLQRQHVSPDYTDVPDIVCQDYAVPHMQQLLPNAPPC 630
             ||||:||||||||.||||||||.|.|:|:||.|::||||||||||||:|||||||.|:|..|
Mosquito   506 -SIDKSSLYHEPFNVNMYTSAASGCSMSDMQRHHITPDYTDVPDIVCQEYAVPHMQDLIPKIP-- 567

  Fly   631 GSGCGTGTGTGPGRGSSPEFVVATGKVTASARNSLNAATLPLPSPPVPPPLEKYYAATPVSSKPM 695
                          |.     ..:.::|....|::    .|.| ||||||.|||||||.:.....
Mosquito   568 --------------GG-----YVSVRLTPPTLNNI----FPKP-PPVPPPPEKYYAATAICKSST 608

  Fly   696 PVAPPGSQSSGSLSSSTTAATTPTSGVVGVGKPHHYNLDMSANFADINEERANCQVQEFPRQSLV 760
            ....|.:|..........|               :.:||:..:..|:       |:.|:||..||
Mosquito   609 TPTTPSNQQQQQQQQQLNA---------------YSDLDLGVSDDDL-------QLSEYPRDKLV 651

  Fly   761 IVEKLGSGVFGELHLCETNVLNATLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGAC 825
            ||||||.|.|||||||||...:..||||:||||||:||::||||||||||::|:|||:.:|:|||
Mosquito   652 IVEKLGCGAFGELHLCETKGYSTNLVAVSTLRPGASDHMKKEFRSKAKQLSRLNDPNIVKLLGAC 716

  Fly   826 LRDEPICIVQDYSHCLGDLNQFLQEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVH 890
            |:|||||||.||.... |||||||||.|||..|:...|||:|||:|||||||||||:|||||.||
Mosquito   717 LKDEPICIVLDYKFST-DLNQFLQEHTAETGSLVQHNSLSYGCLIYIATQIASGMKYLEQMNVVH 780

  Fly   891 RDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAWESVLLGKFTT 955
            ||||||||::||:|.:|:|::||||||.||.:|||.||| .||||||||||||||||||:||||:
Mosquito   781 RDLATRSCLVGPQLEIKICTLGTVINRIAYPADYCHLEG-AGRQSQPMPIRWMAWESVLMGKFTS 844

  Fly   956 KSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCEC 1020
            |||||||||.||||||||||||:|:|||..||||||.:|:|.|.|.|||:|..|||||:||||||
Mosquito   845 KSDVWSFAVTLWEILTFAREQPFENLSDDKVIENIGHMYQDNKKHILLPIPVGCPREIFDLMCEC 909

  Fly  1021 WQRDESSRPSFREIHLYLQRKNLGFKPQTHT 1051
            |||:|:|||:||||||:||||||.   |.||
Mosquito   910 WQRNEASRPNFREIHLFLQRKNLA---QPHT 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddr	NP_001014474.3	FA58C	109..261	CDD:238014	117/151 (77%)
		PTKc_DDR	753..1040	CDD:270644	211/286 (74%)
Ddr	XP_061511090.1	None