DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ddr and dnt

DIOPT Version :9

Sequence 1:	NP_001014474.3	Gene:	Ddr / 3346209	FlyBaseID:	FBgn0053531	Length:	1054	Species:	Drosophila melanogaster
Sequence 2:	NP_001260567.1	Gene:	dnt / 35207	FlyBaseID:	FBgn0024245	Length:	584	Species:	Drosophila melanogaster

Alignment Length:	355	Identity:	90/355 - (25%)
Similarity:	155/355 - (43%)	Gaps:	66/355 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   699 PPGSQSSGSLSSSTTAATTPTSG-----VVGVGKPHHYNLDMSANFADINEERANCQVQEFPRQS 758
            ||...|.||.:..|.:...|..|     .|.|.....:..::....:::..||  |:|    |.|
  Fly   262 PPCQSSMGSAAYMTPSIIAPIHGSSLPRKVPVSVEQQHPEELHRRISELTVER--CRV----RLS 320

  Fly   759 LVIVEKLGSGVFGELHLCETNVLNATLVAVATLRPGANDHLRKEFRSKAKQLAQL---------- 813
            .::.|    |.||.::   ....|.|           .|.|.|.....|.|:..|
  Fly   321 SLLQE----GTFGRVY---RGTYNDT-----------QDVLVKTVAQHASQMQVLLLLQEGMLLY 367

  Fly   814 --SDPNVARLVGACLRDE--PICIVQDYSHCLGDLNQFLQEHVAETSGLMAKKSLSFGCLVYIAT 874
              |.|.:..::|..:.|.  |..:....:: ..:|.|||.:..       ..::::...:|.:|:
  Fly   368 GASHPGILSVLGVSIEDHTTPFVLYPALNN-TRNLKQFLLDPA-------CARTVTTIQIVMMAS 424

  Fly   875 QIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQPMP 939
            |::..:.||.....||:|:|||:|:|..:|.||:..  :.::|..:.|||..|     ..|:..|
  Fly   425 QLSMALDHLHSHGVVHKDIATRNCVIDDQLRVKLSD--SSLSRDLFPSDYNCL-----GDSENRP 482

  Fly   940 IRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLP 1004
            ::||:.|::...:|:..||.|:|.|.:||:.|.|: |||..:....:...:...||       |.
  Fly   483 VKWMSLEALQHKQFSEASDSWAFGVLMWELCTSAK-QPYAEVDPFEMEHYLKDGYR-------LA 539

  Fly  1005 MPPNCPREIYDLMCECWQRDESSRPSFREI 1034
            .|.|||.|::.:|..||....:.||:|.::
  Fly   540 QPFNCPDELFTIMAYCWALLPAERPTFAQL 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ddr	NP_001014474.3	FA58C	106..262	CDD:214572
		FA58C	109..261	CDD:238014
		PTKc_DDR	753..1040	CDD:270644	76/296 (26%)
		TyrKc	759..1038	CDD:197581	74/290 (26%)
dnt	NP_001260567.1	WIF	46..182	CDD:128745
		PKc_like	310..580	CDD:304357	80/307 (26%)
		Pkinase_Tyr	317..573	CDD:285015	77/298 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030