Protein Alignment Ddr and ephb4a

DIOPT Version :10

• Sequence 1: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Sequence 2: NP_571489.1
• Gene: ephb4a / 30688
• ZFINID: ZDB-GENE-990415-62
• Length: 987
• Species: Danio rerio
• Alignment Length: 298
• Identity: 97/298 - (32%)
• Similarity: 158/298 - (53%)
• Gaps: 32/298 - (10%)

  Fly   745 ERANCQVQEFPRQ---SLVIVEK-LGSGVFGELHLCETNV----LNATLVAVATLRPGANDHLRK 801
            |..|..|:||.::   |.|.:|: :|:|.|||  :|...:    .....||:.||:.|..|..|:
Zfish   603 EDPNEAVREFAKEIDVSCVKIEEVIGAGEFGE--VCRGRLRIPGKKENYVAIKTLKGGYTDKQRR 665

  Fly   802 EFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFLQEHVAETSGLMAKKSLSF 866
            :|.::|..:.|...||:..|.|......|:.|:.::.. .|.|:.||:.:..:.:.:.
Zfish   666 DFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFME-NGALDSFLRLNDGQFTPIQ------- 722

  Fly   867 GCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFT 931
              ||.:...||||||:|.:|::||||||.|:.::...|..||...|.    |.:..:......:|
Zfish   723 --LVGMLRGIASGMKYLSEMSYVHRDLAARNILVNSNLVCKVSDFGL----SRFLQENSSDPTYT 781

  Fly   932 GRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRD 996
            ......:||||.|.|::...|||..|||||:.:.:||:::|. |:||..:|::.|   |..|.:|
Zfish   782 SSLGGKIPIRWTAPEAIAFRKFTCASDVWSYGIVMWEVMSFG-ERPYWDMSNQDV---INAIEQD 842

  Fly   997 YKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREI 1034
            |:    ||.||:|...::.||.:|||::.::||.|..|
Zfish   843 YR----LPPPPDCSTYLHQLMLDCWQKERTARPRFANI 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddr	NP_001014474.3	FA58C	109..261	CDD:238014
		PTKc_DDR	753..1040	CDD:270644	94/290 (32%)
ephb4a	NP_571489.1	EphR_LBD	26..199	CDD:470656
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	319..340
		fn3	339..418	CDD:394996
		FN3	440..533	CDD:238020
		EphA2_TM	547..618	CDD:464211	5/14 (36%)
		PTKc_EphR_B	616..884	CDD:173638	92/285 (32%)
		SAM_EPH-B4	914..980	CDD:188953