Protein Alignment Ddr and ddr1

DIOPT Version :9

• Sequence 1: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Sequence 2: XP_002939505.1
• Gene: ddr1 / 100488573
• XenbaseID: XB-GENE-485346
• Length: 946
• Species: Xenopus tropicalis
• Alignment Length: 1040
• Identity: 341/1040 - (32%)
• Similarity: 499/1040 - (47%)
• Gaps: 181/1040 - (17%)

  Fly    63 LCWLTLTLILLANRFGMGTAVGTPETPAAVGSNGLLAEMPIGTCKQALGMESGAIADFQITASSA 127
            |.|..|.|.|         .:..|:           |.....:|:.||||:...|.|..||||||
 Frog    10 LFWFNLLLAL---------CIAEPD-----------AHFDPSSCRYALGMQDRTIPDEDITASSA 54

  Fly   128 HDMGNVGPQHARLKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTE 192
            .. .:...:|:||:.::..|||||...|.....|:|||||..:|.::.:.||||.|.|.|:|:..
 Frog    55 WS-DSTEAKHSRLESNDGDGAWCPLGPVFPNYEEFLQVDLRNLHFLTLVGTQGRDGGGLGKEFAR 118

  Fly   193 AYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRA 257
            .|.:.|.|.|. ||.:||...|.||:.||.||:..|...|.|.:.|..||.||.:....:||||.
 Frog   119 HYQLRYSRDGF-KWSQWRDRWGNEVIEGNENTHDSVLKDLGPPIIARYVRFYPMADRVMSVCLRV 182

  Fly   258 EIVGCAWEEGIVSYSIPKG---MQRGMDIDLSDKTYDGYEEGDHYVNGLGQLVDGQRGKDNF-RA 318
            |:.||.|::|:.||:.|.|   ....|.|:|:|.||||:..|.....|||||.||..|.|:| :.
 Frog   183 ELYGCIWQDGLRSYTSPPGNVMSLPSMLINLNDSTYDGFTVGGLQYGGLGQLTDGVIGADDFLQH 247

  Fly   319 DINGLGKGYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGG 383
            ...|:..||:::||.........:|:.|||:.:|:...:.:|.|||.|..:|:|.....:|. ..
 Frog   248 KEQGVWPGYDYVGWMTSNFPKGYLEMEFEFDALRSFIYMRVHCNNMGSGGIQIFRRVDCYFK-RS 311

  Fly   384 RH--FSGEPVQFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPVVGNF 446
            .|  :..:||..|...|:....||.|||.|..|..|.::.|.||:::|:::|||:|:|..:....
 Frog   312 LHTPWDPQPVTLSLALDVRDPSARSVTIALQGRAARILRCHYYFSSQWLLLSEISFLSDILDATD 376

  Fly   447 TDE-------LANGEKQSVTSEYPLQRDEVGRAISSGGERSQHTTQVISP-------KPIDHQEP 497
            .:|       :.......|||   :.:|...|..:|.|..:.....|:..       :||  .:.
 Frog   377 PEEPSPLPPPMQTIPPPEVTS---IPQDTTKRETTSTGTTASLNGHVLEAGIDIRMNQPI--AKD 436

  Fly   498 ETSFVGVIITVLGTIIMLLVAFILLIVARNKHVRSRENGLDAFQHNFSPDTLNGNGVLKVVTTMD 562
            ::....::|..|..||:||:..|:||:.|.:..|.    |...|...|...|..:..|...|.:.
 Frog   437 DSGDTSILIGCLVVIILLLLVVIILILWRQRWKRL----LGKAQRRPSDSDLTAHLSLPTDTVVI 497

  Fly   563 DN--------------ESSIDKNSLYHEPFN---ANMYT----SAASACPMNDLQRQHVSPDYTD 606
            :|              |..|.....|.||.:   |.:.|    |..:|..:|       :|.|
 Frog   498 NNTHNAPGPPRHANRYERIITSEGEYQEPSHNPRAKITTLSLSSEGAALLLN-------NPAY-- 553

  Fly   607 VPDIVCQDYAVPHMQQLLPNAPPCGSGCGTGTGTGPGRGSSPEFVVATGKVTASARNSLNAATLP 671
              :::...|:.|                                :...|.:.|...||.......
 Frog   554 --ELLLTTYSRP--------------------------------ITEHGGLQAKPINSQEGGYRE 584

  Fly   672 LPSPPVP---PPLEKYYAATPVSSKPMPVAPPGSQSSGSLSSSTTAATTPTSGVVGVGKPHHYNL 733
            |.:|.:|   ||...:||...:.:           ..|....:|.|....|:..:.
 Frog   585 LETPKLPACCPPSVPHYAEADIVT-----------LQGVTGGNTYAVPALTADSLA--------- 629

  Fly   734 DMSANFADINEERANCQVQEFPRQSLVIVEKLGSGVFGELHLCETNVLN---------------- 782
                     :::...|   :|||..|:..||||.|.|||:||||  |:|
 Frog   630 ---------SKDLPLC---KFPRGHLLFKEKLGEGQFGEVHLCE--VVNPHELPTLQFPFNMRKG 680

  Fly   783 -ATLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQ 846
             :.||||..||..||.:.|.:|..:.|.|::||||::.||:||||.::|:|::.:|.. .|||||
 Frog   681 RSLLVAVKLLRADANKNARSDFLKELKILSRLSDPHIIRLLGACLDEDPLCMITEYME-NGDLNQ 744

  Fly   847 FLQEH---VAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKV 908
            ||..|   ..|.||.....::|:..|:::|.||.||||:|..:||||||||:|:|::|....:|:
 Frog   745 FLSSHHLDEGEESGAQCLPAISYPSLLHVAVQICSGMKYLSSLNFVHRDLASRNCLVGENFTIKI 809

  Fly   909 CSIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFA 973
            ...|  ::|:.||.||.:::|     ...:||||||||.:|:|||||.||||:|.|.|||||...
 Frog   810 ADFG--MSRNLYAGDYYRIQG-----RAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEILMLC 867

  Fly   974 REQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYL 1038
            :||||..|||:.||||.|.|:||.|....|..||.||:.:|:||.:||.||...||||::||..|
 Frog   868 KEQPYGELSDEDVIENAGEIFRDSKKQIFLFRPPPCPQPLYELMLQCWSRDCRERPSFQDIHALL 932

  Fly  1039  1038
             Frog   933  932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddr	NP_001014474.3	FA58C	106..262	CDD:214572	65/155 (42%)
		FA58C	109..261	CDD:238014	64/151 (42%)
		PTKc_DDR	753..1040	CDD:270644	143/306 (47%)
		TyrKc	759..1038	CDD:197581	139/298 (47%)
ddr1	XP_002939505.1	FA58C	35..186	CDD:238014	64/152 (42%)
		PTKc_DDR1	637..934	CDD:133227	143/306 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	270	1.000	Domainoid score	I1800
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	525	1.000	Inparanoid score	I1217
OMA	1	1.010	-	-		QHG45751
OrthoDB	1	1.010	-	-		D122892at33208
OrthoFinder	1	1.000	-	-		FOG0001292
OrthoInspector	1	1.000	-	-		mtm9464
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X998
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080