DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr3 and KIRREL1

DIOPT Version :9

Sequence 1:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	XP_005245362.1	Gene:	KIRREL1 / 55243	HGNCID:	15734	Length:	773	Species:	Homo sapiens

Alignment Length:	207	Identity:	44/207 - (21%)
Similarity:	75/207 - (36%)	Gaps:	62/207 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 RFQVTESKDSREWTLHVKAPLAKDSGIYECQVNTEPKMSMAFQLNIIEISPDAKAVISGPPDLHF 356
            |::|..|.|:.::.|.:......|...||||.......|...:|.::....|.:  |.|.|.:..
Human    71 RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTR--IDGGPVILL 133

  Fly   357 KAGSAIILNCLVQQPSVKDIGPIYWYR------------------------GEHMITPFDADDGQ 397
            :||:...|.|  :..:.|....|.|:|                        .:.:|.|.|.|.|:
Human   134 QAGTPHNLTC--RAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGR 196

  Fly   398 --------PEIPAGRGEHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQLGDTLKSRLRISNAQ 454
                    ..||:|:         :||     .|:|:.......:::|.|   |::...|:.
Human   197 VFTCRSMNEAIPSGK---------ETS-----IELDVHHPPTVTLSIEPQ---TVQEGERVV--- 241

  Fly   455 TTDTGNYTCQPT 466
                  :|||.|
Human   242 ------FTCQAT 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	10/37 (27%)
		IG_like	243..329	CDD:214653	10/36 (28%)
		Ig	350..464	CDD:299845	27/145 (19%)
		IG_like	<441..477	CDD:214653	6/26 (23%)
KIRREL1	XP_005245362.1	I-set	22..116	CDD:254352	12/44 (27%)
		Ig	25..116	CDD:299845	12/44 (27%)
		Ig2_KIRREL3-like	138..219	CDD:143236	17/96 (18%)
		I-set	223..304	CDD:254352	8/37 (22%)
		Ig_2	227..305	CDD:290606	8/33 (24%)
		Ig_2	311..405	CDD:290606
		IG_like	314..405	CDD:214653
		Ig5_KIRREL3	407..504	CDD:143306
		IG_like	416..504	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810