DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr3 and Ntm

DIOPT Version :9

Sequence 1:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:357 Identity:82/357 - (22%)
Similarity:136/357 - (38%) Gaps:100/357 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   233 QSLPI--FDFGMPR---NITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKR 292
            |.:|:  .|...|:   |:|.|.|.: |.::|.:|:...: |:|:.:..  ||..|...:..|.|
  Rat    27 QGVPVRSGDATFPKAMDNVTVRQGES-ATLRCTIDNRVTR-VAWLNRST--ILYAGNDKWCLDPR 87

  Fly   293 FQVTESKDSREWTLHVKAPLAKDSGIYECQVNTE--PKMSMAFQLNIIEISPDAKAVISGPPDLH 355
            . |..|....::::.::.....|.|.|.|.|.|:  ||.|....  |:::||....:.|   |:.
  Rat    88 V-VLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHL--IVQVSPKIVEISS---DIS 146

  Fly   356 FKAGSAIILNCLV---QQPSVKDIGPIYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSP 417
            ...|:.|.|.|:.   .:|:|.      |.........|.::|...|| .|......|..|.::.
  Rat   147 INEGNNISLTCIATGRPEPTVT------WRHISPKAVGFVSEDEYLEI-QGITREQSGEYECSAS 204

  Fly   418 NDIMSEV----------------------------DLQMEFAT------------RIAMESQLGD 442
            ||:.:.|                            .||.|.:.            :..:|.:.|.
  Rat   205 NDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGV 269

  Fly   443 TLK-----SRLRISNAQTTDTGNYTCQPTTA---SSASVLVHVIND------------------E 481
            .::     |||...|....|.|||||..:..   ::||:::..:|:                  :
  Rat   270 KVENRPFLSRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPWK 334

  Fly   482 NPAAMQK-----SGACPCA-LGPLQLLLHLLL 507
            .|.|:.:     |....|. |.|| |:|||||
  Rat   335 GPGAVSEVNNGTSRRAGCIWLLPL-LVLHLLL 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr3NP_001014459.2 Ig 243..330 CDD:299845 25/91 (27%)
IG_like 243..329 CDD:214653 24/90 (27%)
Ig 350..464 CDD:299845 32/161 (20%)
IG_like <441..477 CDD:214653 13/43 (30%)
NtmXP_017451354.1 Ig 44..132 CDD:416386 25/94 (27%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 2/8 (25%)
CDR1 59..63 CDD:409353 1/3 (33%)
FR2 64..70 CDD:409353 2/6 (33%)
Ig strand C 64..70 CDD:409353 2/6 (33%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 8/34 (24%)
Ig strand D 87..94 CDD:409353 3/7 (43%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 3/10 (30%)
FR4 125..132 CDD:409353 1/8 (13%)
Ig_3 136..205 CDD:404760 17/78 (22%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand F 197..205 CDD:409353 2/7 (29%)
Ig 223..307 CDD:416386 15/83 (18%)
putative Ig strand A 223..229 CDD:409353 0/5 (0%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 3/3 (100%)
Ig strand F 292..297 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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