DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr3 and klg

DIOPT Version :9

Sequence 1:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	320	Identity:	69/320 - (21%)
Similarity:	122/320 - (38%)	Gaps:	73/320 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 LDASFGSDLFAQTDAKRERSGAADEESQDADTSQSLPIFDFGMPRNITGRTGHT-------EAII 257
            |.|..||..||...|...|...:...|....::.:.......:||.::  .|||       ..::
  Fly    58 LHAHAGSGGFAVEAAISNRGSNSRSMSNVQQSAVAASTLTATLPRFLS--RGHTYRAVVGDTLVL 120

  Fly   258 KCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQ 322
            .|:|::|.:..:.|  :|..::||......|.|:|.::.:.     :.|.:.....:|:|.|.||
  Fly   121 PCQVENLGNFVLLW--RRGTNVLTASNIMVTRDERVRLIDG-----YNLEISDLEPQDAGDYVCQ 178

  Fly   323 VNTEPKMSMAFQLNIIEISPDAKAV-ISGPPDLHFKAGSAIILNCLVQQPSVKDIGPIYWYR--G 384
            ::.:........:.|: :.|..:|: .||  .|..:.|..|.|.|   :.|...:..|||.:  |
  Fly   179 ISDKINRDQVHTVEIL-VPPSVRAIPTSG--QLQARKGGPITLEC---KGSGNPVPSIYWTKKSG 237

  Fly   385 EHMITPFDADDGQPEIPAGRGEHPQ-GIPEDTSPN------------DIMSEVDLQME------- 429
            .:..|....|.  |.:...:.|..| |:.:.|:.|            |::...|:|:|
  Fly   238 ANKSTARIGDG--PILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSG 300

  Fly   430 -----------FATRIAMESQLGDTL---------------KSRLRISNAQTTDTGNYTC 463
                       ||..:|..|...::.               :..|.|.:.|..|.|||:|
  Fly   301 EGFEAKLVCIVFADPVATVSWYQNSFPIQSTDRRIMATRANRHMLTIRHIQQEDFGNYSC 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	21/93 (23%)
		IG_like	243..329	CDD:214653	21/92 (23%)
		Ig	350..464	CDD:299845	35/162 (22%)
		IG_like	<441..477	CDD:214653	8/38 (21%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	13/62 (21%)
		IG_like	109..195	CDD:214653	18/93 (19%)
		Ig	118..191	CDD:143165	16/79 (20%)
		IG_like	205..274	CDD:214653	20/75 (27%)
		IGc2	213..273	CDD:197706	17/64 (27%)
		IGc2	301..367	CDD:197706	12/60 (20%)
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810