DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr3 and dpr17

DIOPT Version :9

Sequence 1:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	474	Identity:	129/474 - (27%)
Similarity:	202/474 - (42%)	Gaps:	113/474 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 AAAAAGATTSVAATAAAAAAATTRAAATTRAVIIIMALVV-----------SIMQQQQQSLLWPF 126
            |..|:.||.:.|||:||.:||...|||.|.....::...:           ||.:.:.|
  Fly   243 AQTASTATQAAAATSAATSAAIASAAAATETAAEMLISTIYPASTETDLHNSIERVEGQ------ 301

  Fly   127 CNGLAAAAASTGQPDDSGDGPTLSTFL----------------SSSQSQSPSPPAASASASSPSS 175
             .|..|.|...|.||....|.::.|||                ::..:::....|.:|:.::.:.
  Fly   302 -RGKMANAFHPGVPDSLTKGFSIPTFLPPFPVFAAADLPAYRAAADAAEAAKLAAEAAAQAAAAK 365

  Fly   176 FSSFAVAHGPQTEATNHTFKSLAFLDASFGSDLFAQTDAKRERSGAADEESQDADTSQSLPIFDF 240
            .||.||...|:.:......:..::|.|              .|.| .|........:.::|:.
  Fly   366 TSSEAVTMSPEEQRRQMFNEQHSYLAA--------------HRDG-GDGAGSAVRRNLTMPVL-- 413

  Fly   241 GMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKD-SREW 304
                |||.:.|: .|.:.|::..|.||.|||:|.||.||::|...|:.:|:|||....:| ...|
  Fly   414 ----NITAQMGN-HAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTW 473

  Fly   305 TLHVKAPLAKDSGIYECQVNTEPKMSMAFQLNIIEISPDAKAVISGPPDLHFKAGSAIILNCLVQ 369
            :|.:|.....|:|.||||:.||||:|....|.|::    .|..:.|......||||.:.|:|:|:
  Fly   474 SLQIKYVEPSDAGWYECQMATEPKLSAKVHLQIVK----PKTELIGDQSRFVKAGSKVALHCIVR 534

  Fly   370 QPSVKDIGP---IYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDIMSEVDLQMEFA 431
                ..:.|   |.|:||:..|:..|...|.                       .:::|..: |.
  Fly   535 ----GTLDPPKYIIWFRGQKKISDSDERTGW-----------------------YTQLDRNI-FG 571

  Fly   432 TRIAMESQLGD---TLKSRLRISNAQTTDTGNYTCQPTTASSASVLVHVINDENPAAMQKSGA-- 491
            |       :||   |:.| |.|...:..|:|||||||:.:.|.||.:||::.|..|:...|.|
  Fly   572 T-------VGDNQNTIGS-LIIPLVRKEDSGNYTCQPSNSVSVSVDLHVLSGEYSASAIMSTAAR 628

  Fly   492 --------CPCALGPLQLL 502
                    |...||.|.:|
  Fly   629 TTKGGRSTCHSTLGLLGIL 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	37/87 (43%)
		IG_like	243..329	CDD:214653	36/86 (42%)
		Ig	350..464	CDD:299845	30/119 (25%)
		IG_like	<441..477	CDD:214653	17/38 (45%)
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	31/77 (40%)
		Ig	415..507	CDD:299845	38/92 (41%)
		IG_like	521..612	CDD:214653	35/126 (28%)
		IGc2	524..605	CDD:197706	30/116 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444688
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D104656at50557
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850