DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr3 and Lac

DIOPT Version :9

Sequence 1:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:338 Identity:65/338 - (19%)
Similarity:104/338 - (30%) Gaps:103/338 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   232 SQSLPIFDFGMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIR-KRDLHILTVGTATYTSDKRFQV 295
            :|..|...:.....|....|..|  ..|.|....:.:|.::: ..|...|:.|:.....|.||.:
  Fly    25 AQRTPTISYITQEQIKDIGGTVE--FDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSL 87

  Fly   296 TESKDSREWTLHVKAPLAKDSGIYECQVNTEPKMSMAFQLNIIEISPDAKAVISGPPDLHFKA-- 358
            ....:|..:.|.:|.....|:|.|.|||...         .:.::|.:.|..:..||.:...:  
  Fly    88 RYDPNSSTYKLQIKDIQETDAGTYTCQVVIS---------TVHKVSAEVKLSVRRPPVISDNSTQ 143

  Fly   359 ------GSAIILNCLVQ---QPSVKDIGPIYWYRGEHMITPFD---------------------- 392
                  ||.:.:.|...   .|:      |.|.|..:.|.|.|                      
  Fly   144 SVVASEGSEVQMECYASGYPTPT------ITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTY 202

  Fly   393 ---ADDG---------------QPEIPAGRGEHPQGIPEDTS----------PNDIMSEVDLQM- 428
               ||:|               .|.|...|....|.:..|..          |..:.::.|:|: 
  Fly   203 YCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLA 267

  Fly   429 --------EFATRIAMESQLGDTLKSRLRISNAQTTDTGNYTCQPTTA-SSASVLVHVINDENPA 484
                    .|||       ..:...|.||:...:....|:|.|:.|.. ..|...|::.....| 
  Fly   268 NNQHYSISHFAT-------ADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIP- 324

  Fly   485 AMQKSGACPCALG 497
                  .||.|.|
  Fly   325 ------VCPPACG 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr3NP_001014459.2 Ig 243..330 CDD:299845 21/87 (24%)
IG_like 243..329 CDD:214653 21/86 (24%)
Ig 350..464 CDD:299845 31/183 (17%)
IG_like <441..477 CDD:214653 9/36 (25%)
LacNP_523713.2 IG_like 36..131 CDD:214653 23/105 (22%)
FR1 37..50 CDD:409353 3/14 (21%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 2/8 (25%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 9/30 (30%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 0/16 (0%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 13/79 (16%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/9 (11%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 0/4 (0%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 19/97 (20%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.