DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr3 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	83/397 - (20%)
Similarity:	133/397 - (33%)	Gaps:	134/397 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 KSLAFLDASFGSDLFAQTDAKRERSGAADEESQDADTSQSLPIFDFGMPRNITGRTGHTEAIIKC 259
            :|:.|..|||                   .|..::|...|.||.:..:|   .||    :|::.|
  Fly    14 QSVCFSQASF-------------------SELNNSDPKFSGPINNSTVP---VGR----DALLTC 52

  Fly   260 RVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQVN 324
            .|..|....|:|:|.....||::.....|.:.|..::.: :.|.|.|.::.....|.|.|.||:|
  Fly    53 VVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHT-EHRIWQLKIRDVQESDRGWYMCQIN 116

  Fly   325 TEPKMSMAFQLNIIEISPDAKAVISGPPDLHFKAGSAIILNCL---VQQPSVKDIGPIYWYRGEH 386
            |:|..|....|::: :.||. .......|:....|..:.|.|.   |..|:      |.|.|.|
  Fly   117 TDPMKSQMGYLDVV-VPPDI-VDYQTSQDVVRSTGQNVTLTCSATGVPMPT------ITWRREE- 172

  Fly   387 MITP-FDADDGQPEIPAGRGEH------------------PQGIPEDTSPNDIMSEVDLQMEFAT 432
             .|| ..:|||..|:.:..|::                  ..|:|...|     ..|.|.:.||.
  Fly   173 -ATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVS-----KRVMLVVNFAP 231

  Fly   433 RI-------------------------------AMESQL--GDTLKS-----------RLRISNA 453
            .|                               ..:|||  |.:.:|           |:.:...
  Fly   232 TIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGGSYESVSVDHVFRIVMRITLRPI 296

  Fly   454 QTTDTGNYTCQPTTASSAS---VLVH--------------------VINDENPAAMQKSGACPCA 495
            ...|.|.|.|:...|...:   :.||                    ::.:|..|.|....   |:
  Fly   297 TKRDFGEYICRAKNAMGQTDRIITVHHKAKKHGQHSHQTSSRESQFIVIEEYIANMSDKS---CS 358

  Fly   496 LGPLQLL 502
            ..||.::
  Fly   359 FQPLWIM 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	25/86 (29%)
		IG_like	243..329	CDD:214653	25/85 (29%)
		Ig	350..464	CDD:299845	34/179 (19%)
		IG_like	<441..477	CDD:214653	10/69 (14%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	26/93 (28%)
		Ig	39..122	CDD:299845	25/90 (28%)
		Ig	132..213	CDD:299845	19/89 (21%)
		IG_like	141..227	CDD:214653	22/98 (22%)
		IG_like	239..322	CDD:214653	11/82 (13%)
		IGc2	245..313	CDD:197706	11/67 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810