DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr3 and Sdk1

DIOPT Version :9

Sequence 1:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_808547.3 Gene:Sdk1 / 330222 MGIID:2444413 Length:2193 Species:Mus musculus


Alignment Length:445 Identity:92/445 - (20%)
Similarity:149/445 - (33%) Gaps:176/445 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 LSTFLSSSQSQSPSPPAASASASSPSSFSSFAVAHGPQTEAT----NH----------TFKSLAF 199
            :..|:.:.|.::.|...|:.....|       :...||.:.|    .|          |.::...
Mouse   172 MGNFMDTDQRKTVSQGHAALLNLLP-------IVSCPQPQVTWFREGHKIIPSSRIAITLENQLV 229

  Fly   200 LDASFGSDLFA-QTDAKRERSGAADEE-------SQDADTSQSLPIFDFGMPRNITGRTGHTEAI 256
            :.|:..||..| ...|..|::|.....       ::|..|.:::.......|.|.:...|.:|..
Mouse   230 ILATTASDAGAYYVQAVNEKNGENKTSPFIHLSVARDTGTHEAMAPIIVVAPGNRSVVAGSSETT 294

  Fly   257 IKCRVDS--LHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDSGIY 319
            ::|..::  :.:.||.|  ||:...||.|..:|  .:|..:|.             |.:.|:|:|
Mouse   295 LECIANARPVEELSVHW--KRNGVRLTSGLHSY--GRRLTITN-------------PTSADTGMY 342

  Fly   320 ECQVNT-----EPKMSMAFQLNIIEISPDAKAVISGPPDLHFKAGSAIILNCLVQQPSVKDIGPI 379
            .|:...     ||..:.|| |:|||           ||  :|.|           :|..:.:|.:
Mouse   343 VCEATLRGSTFEPARARAF-LSIIE-----------PP--YFTA-----------EPESRILGEV 382

  Fly   380 ------------------YWYRGEHMITPFDADDGQP----------EIPAGRGEHPQ------- 409
                              .||:           |..|          .:|:| |.|.|       
Mouse   383 EETMDIPCRAMGVPLPTLQWYK-----------DAVPLSKLQNPRYKVLPSG-GLHIQKLSPEDS 435

  Fly   410 GI------------------------------PEDTSPNDIMSEVDLQMEF--ATRIAMESQLGD 442
            ||                              |.||:..|.|:.| |:.|.  |.:.|:..:.|:
Mouse   436 GIFQCFASNEGGEVQTHTYLDVTNIAPAFTQRPVDTTVTDGMTAV-LRCEVSGAPKPAITWKRGN 499

  Fly   443 TL---------------KSRLRISNAQTTDTGNYTCQP--TTAS-SASVLVHVIN 479
            .:               ...|||:.....|.|||||..  |.|| :||.::.|.|
Mouse   500 HILASGSVRIPRFMLLESGGLRIAPVFIQDAGNYTCYAANTEASVNASAMLTVWN 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr3NP_001014459.2 Ig 243..330 CDD:299845 23/93 (25%)
IG_like 243..329 CDD:214653 23/92 (25%)
Ig 350..464 CDD:299845 36/195 (18%)
IG_like <441..477 CDD:214653 15/53 (28%)
Sdk1NP_808547.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56
Ig_2 94..169 CDD:290606
IG_like 100..169 CDD:214653
IG_like 183..263 CDD:214653 15/86 (17%)
Ig 197..247 CDD:299845 10/49 (20%)
IG_like 281..357 CDD:214653 23/92 (25%)
IGc2 294..347 CDD:197706 17/69 (25%)
I-set 368..457 CDD:254352 16/113 (14%)
Ig 388..454 CDD:143165 11/77 (14%)
I-set 462..552 CDD:254352 25/90 (28%)
Ig 476..552 CDD:299845 21/76 (28%)
I-set 557..646 CDD:254352
Ig 562..646 CDD:299845
FN3 650..741 CDD:238020
fn3 753..839 CDD:278470
FN3 854..949 CDD:238020
FN3 954..1036 CDD:238020
FN3 1052..1148 CDD:238020
FN3 1158..1253 CDD:238020
FN3 1261..1349 CDD:238020
FN3 1360..1453 CDD:238020
FN3 1459..1554 CDD:238020
FN3 1562..1676 CDD:238020
FN3 1686..1779 CDD:238020
FN3 1784..1865 CDD:238020
FN3 1885..1978 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2057..2080
PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 2187..2193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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