DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr3 and Negr1

DIOPT Version :9

Sequence 1:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:299 Identity:60/299 - (20%)
Similarity:112/299 - (37%) Gaps:83/299 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   238 FDFGMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSR 302
            |.:....|:..|.|.| |:::|.::....|. :|:.:..  |:..|...::.|.|..:: :.:.|
Mouse    34 FPWAAVDNMLVRKGDT-AVLRCYLEDGASKG-AWLNRSS--IIFAGGDKWSVDPRVSIS-TLNKR 93

  Fly   303 EWTLHVKAPLAKDSGIYECQVNTE--PKMSMAFQLNI-IEISPDAKAVISGPPDLHFKAGSAIIL 364
            :::|.::.....|.|.|.|.|.|:  |:   ..|::: :::.|....:.:   |:....|:.:.|
Mouse    94 DYSLQIQNVDVTDDGPYTCSVQTQHTPR---TMQVHLTVQVPPKIYDISN---DMTINEGTNVTL 152

  Fly   365 NCLVQQPSVKDIGPIYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDI----MSEVD 425
            .||.   :.|....|.|........||  ::||.....|......|..|.::.||:    :.:|.
Mouse   153 TCLA---TGKPEPVISWRHISPSAKPF--ENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVR 212

  Fly   426 LQMEFATRI--------------------------AMESQLGD---------------TLKSRLR 449
            :.:.||..|                          |.|...|:               :.:|.|.
Mouse   213 VIVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILT 277

  Fly   450 ISNAQTTDTGNYTC-------------------QPTTAS 469
            ::|......|||||                   :|||:|
Mouse   278 VTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSS 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr3NP_001014459.2 Ig 243..330 CDD:299845 21/88 (24%)
IG_like 243..329 CDD:214653 21/87 (24%)
Ig 350..464 CDD:299845 32/177 (18%)
IG_like <441..477 CDD:214653 13/63 (21%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 5/17 (29%)
Ig strand A' 40..46 CDD:409353 1/5 (20%)
IG_like 41..129 CDD:214653 22/95 (23%)
Ig strand B 48..56 CDD:409353 3/8 (38%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 2/7 (29%)
Ig strand C 61..67 CDD:409353 2/6 (33%)
CDR2 69..79 CDD:409353 2/11 (18%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 8/35 (23%)
Ig strand D 84..91 CDD:409353 1/7 (14%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 2/11 (18%)
FR4 122..129 CDD:409353 1/6 (17%)
Ig strand A' 139..144 CDD:409353 1/7 (14%)
IGc2 146..204 CDD:197706 16/62 (26%)
Ig strand B 150..157 CDD:409353 3/9 (33%)
Ig strand C 163..168 CDD:409353 2/4 (50%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 1/5 (20%)
Ig strand F 193..200 CDD:409353 2/6 (33%)
Ig_3 219..295 CDD:404760 12/75 (16%)
putative Ig strand A 219..225 CDD:409353 1/5 (20%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 2/3 (67%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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