DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr3 and Ncam2

DIOPT Version :9

Sequence 1:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:324 Identity:68/324 - (20%)
Similarity:109/324 - (33%) Gaps:101/324 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 DAKRERSGAADEESQDADTSQSLPIFDFGMPRNITG----RTGHTEAIIKCRVDSLHDKSVSWIR 273
            ||...|..|.|.:.|..:.:..|.|:.....|.:..    :.|. :|.:.|||.|....:|||:.
  Rat    87 DAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVLSPQEFKQGE-DAEVVCRVSSSPAPAVSWLY 150

  Fly   274 KRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQVNTEPKMSMAFQ--LN 336
            ..:       ..|...|.||.|..:.:     |.:......|.|||.|:...|.:..:.|:  :.
  Rat   151 HNE-------EVTTIPDNRFAVLANNN-----LQILNINKSDEGIYRCEGRVEARGEIDFRDIIV 203

  Fly   337 IIEISPDAKAVISGPPDLHFKA----GSAIILNCLVQ---QPSVKDIGPIYWYRGEHMITP---- 390
            |:.:.|   |::.  |...|.|    |..:.|.|...   .|::.      |:|...:|..    
  Rat   204 IVNVPP---AIVM--PQKSFNATAERGEEMTLTCKASGSPDPAIS------WFRNGKLIEENEKY 257

  Fly   391 --------------FDADDG-----------------------QPEIPAGRGE------------ 406
                          .:.|.|                       ||.|...:.|            
  Rat   258 ILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTSENGHVTLIC 322

  Fly   407 --HPQGIPEDTSPNDI----MSEVDLQMEFATRIAMESQLGDTLKSRLRISNAQTTDTGNYTCQ 464
              ..:.:||.|....|    .||.|...:  .||.::.|.|   :|.|.|.:.:.:|:|.|.|:
  Rat   323 EAEGEPVPEITWKRAIDGVTFSEGDKSPD--GRIEVKGQHG---RSSLHIRDVKLSDSGRYDCE 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr3NP_001014459.2 Ig 243..330 CDD:299845 22/90 (24%)
IG_like 243..329 CDD:214653 22/89 (25%)
Ig 350..464 CDD:299845 33/179 (18%)
IG_like <441..477 CDD:214653 8/24 (33%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452 8/25 (32%)
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452 1/4 (25%)
Ig strand G 104..107 CDD:409452 0/2 (0%)
IGc2 128..189 CDD:197706 20/73 (27%)
Ig strand B 130..139 CDD:409353 3/9 (33%)
Ig strand C 145..153 CDD:409353 3/7 (43%)
Ig strand C' 156..159 CDD:409353 1/2 (50%)
Ig strand D 162..167 CDD:409353 3/4 (75%)
Ig strand E 168..175 CDD:409353 1/11 (9%)
IgI_1_MuSK 209..298 CDD:409562 14/99 (14%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 0/9 (0%)
Ig strand E 264..268 CDD:409562 0/3 (0%)
Ig strand F 278..283 CDD:409562 0/4 (0%)
Ig strand G 291..294 CDD:409562 0/2 (0%)
Ig 300..397 CDD:416386 22/87 (25%)
Ig strand A 300..305 CDD:409353 2/4 (50%)
Ig strand A' 309..313 CDD:409353 1/3 (33%)
Ig strand B 317..325 CDD:409353 0/7 (0%)
Ig strand C 331..337 CDD:409353 2/5 (40%)
Ig strand C' 340..343 CDD:409353 0/2 (0%)
Ig strand D 353..359 CDD:409353 2/5 (40%)
Ig strand E 362..368 CDD:409353 2/5 (40%)
Ig strand F 376..384 CDD:409353 3/6 (50%)
Ig strand G 387..397 CDD:409353
Ig_3 401..479 CDD:404760
Ig strand B 418..422 CDD:409353
Ig strand C 431..435 CDD:409353
Ig strand E 458..462 CDD:409353
Ig strand F 472..477 CDD:409353
Ig strand G 486..489 CDD:409353
FN3 496..588 CDD:238020
fn3 594..678 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.