DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr3 and LRIT1

DIOPT Version :9

Sequence 1:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:286 Identity:63/286 - (22%)
Similarity:90/286 - (31%) Gaps:79/286 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   244 RNITGRTGHTEAIIKCRVDSLHDKSVSWIRK--RDLHILTVGTATYTSDKRFQVTESKDSREWT- 305
            |::.|.|    |:::|....:....:||.|.  |.|:    ||.        ....|.|...|| 
Human   264 RSLLGGT----ALLRCGATGVPGPEMSWRRANGRPLN----GTV--------HQEVSSDGTSWTL 312

  Fly   306 LHVKAPLAKDSGIYECQVNTEPKMSMAFQLNIIEISPDAKAVISGPPD-LHFKAG----SAIILN 365
            |.:.|....|||.|.||.......|... :::|...|......||.|. |..:.|    :|...|
Human   313 LGLPAVSHLDSGDYICQAKNFLGASETV-ISLIVTEPPTSTEHSGSPGALWARTGGGGEAAAYNN 376

  Fly   366 CLV-------QQPSVKDIGPIYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDIMSE 423
            .||       .:|:|...||......|.:.......|...|:..||          ..|::    
Human   377 KLVARHVPQIPKPAVLATGPSVPSTKEELTLEHFQMDALGELSDGR----------AGPSE---- 427

  Fly   424 VDLQMEFATRIAMESQLGDTLKSRLRISNAQTTDTGNYTCQPTTASSASVLVHVINDEN------ 482
                   |..:.....:|||..|...:..|.         |....::.|||..|....:      
Human   428 -------ARMVRSVKVVGDTYHSVSLVWKAP---------QAKNTTAFSVLYAVFGQHSMRRVIV 476

  Fly   483 -PAAMQ----------KSGACPCALG 497
             |...:          |..||.|..|
Human   477 QPGKTRVTITGLLPKTKYVACVCVQG 502

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr3NP_001014459.2 Ig 243..330 CDD:299845 24/88 (27%)
IG_like 243..329 CDD:214653 24/87 (28%)
Ig 350..464 CDD:299845 24/125 (19%)
IG_like <441..477 CDD:214653 9/35 (26%)
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 24/94 (26%)
IG_like 267..345 CDD:214653 24/94 (26%)
FN3 431..498 CDD:214495 13/75 (17%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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