DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr3 and Lrit3

DIOPT Version :9

Sequence 1:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_001274153.1 Gene:Lrit3 / 242235 MGIID:2685267 Length:681 Species:Mus musculus


Alignment Length:269 Identity:52/269 - (19%)
Similarity:99/269 - (36%) Gaps:64/269 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 RSPGHAADVDVAAAAAG--------ATTSVAATAAAAAAATTRAAATTRAVIIIMALVVSIMQQQ 118
            ||.|...:..|...:.|        :.||::...|.......:..|.....::.:.:|..:    
Mouse   289 RSDGSTVNYTVIQESPGEGIRWSIISLTSISHKDAGDYRCKAKNLAGISEAVVTVTVVGGV---- 349

  Fly   119 QQSLLWPFCNGLAAAAASTGQPDD-------SGDGPTLSTFLSSSQSQSPSPPAASAS------- 169
             .:.|.|     .::..|.|:|.:       .|..|...::||...:.:||.|..||:       
Mouse   350 -TTTLSP-----DSSERSPGEPPEQHPQPGLGGSTPPSKSWLSPGLTSAPSYPTPSAALYTSTWS 408

  Fly   170 ---ASSPSSFSSFAVAHGPQTEATNHTFKSLAFLDASFGSDLF---AQTDAKRERSG------AA 222
               :|.|..||:.:.....||..:..|.::      |....|.   .:::||.|::|      :|
Mouse   409 PPPSSLPPIFSAASATTSVQTSISGRTART------SHQPPLLHPGGKSNAKIEKNGRKFPPLSA 467

  Fly   223 DEESQDADTSQSLPIFDFGMPRNIT-------GRTGHTEAIIKCRVDSLHDKSVSWIRKR--DLH 278
            .::.:.|...|:.|     |..|:|       ..||.:..::.....|..:.||:.:..:  :..
Mouse   468 SKKEELALLDQAAP-----METNVTIKDLRVARETGVSVTLMWNSSSSTQESSVTVLYSKYGEKD 527

  Fly   279 ILTVGTATY 287
            :|.|....|
Mouse   528 LLLVNADDY 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr3NP_001014459.2 Ig 243..330 CDD:299845 10/54 (19%)
IG_like 243..329 CDD:214653 10/54 (19%)
Ig 350..464 CDD:299845
IG_like <441..477 CDD:214653
Lrit3NP_001274153.1 LRR 1. /evidence=ECO:0000255 56..79
LRR_8 61..117 CDD:290566
LRR 2. /evidence=ECO:0000255 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3. /evidence=ECO:0000255 104..128
LRR_8 105..165 CDD:290566
LRR_4 106..146 CDD:289563
leucine-rich repeat 107..130 CDD:275378
LRR_4 129..170 CDD:289563
LRR 4. /evidence=ECO:0000255 129..151
leucine-rich repeat 131..154 CDD:275378
LRR 5. /evidence=ECO:0000255 152..175
leucine-rich repeat 155..168 CDD:275378
Ig 254..335 CDD:299845 8/45 (18%)
IG_like 263..339 CDD:214653 9/49 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..391 9/45 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..464 9/44 (20%)
FN3 489..563 CDD:238020 8/48 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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