DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr3 and zig-10

DIOPT Version :9

Sequence 1:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001122644.1	Gene:	zig-10 / 188896	WormBaseID:	WBGene00020800	Length:	322	Species:	Caenorhabditis elegans

Alignment Length:	149	Identity:	41/149 - (27%)
Similarity:	60/149 - (40%)	Gaps:	37/149 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 ADTSQSLPIFDFGMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRF 293
            |.|.:.:||             |.|.| ::|  :.....:|:|.  ||.|::    ||....|..
Worm    30 APTERLVPI-------------GSTTA-LEC--EPYTSSNVTWY--RDKHVI----ATVEGHKNA 72

  Fly   294 QVTESK----DSR--EWTLHVKAPLAK-DSGIYECQVNTEPKMSMAFQLNII---EISPDAKAVI 348
            .:.|.|    :.|  |....|...:.| |.|.|.||...:.|....|||.|.   |||.:.|..:
Worm    73 ILNERKPRGGEERIPEIGFLVIFDVQKEDEGNYYCQRENDSKWGEVFQLKIAYVDEISQNEKIKL 137

  Fly   349 S-GPPDLHFKAGSAIILNC 366
            . ..|.|    |.:::|:|
Worm   138 EPNVPTL----GRSLVLHC 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	24/93 (26%)
		IG_like	243..329	CDD:214653	23/92 (25%)
		Ig	350..464	CDD:299845	5/17 (29%)
		IG_like	<441..477	CDD:214653
zig-10	NP_001122644.1	IG_like	31..118	CDD:214653	27/108 (25%)
		IGc2	38..111	CDD:197706	24/94 (26%)
		IG_like	143..215	CDD:214653	4/14 (29%)
		IGc2	145..209	CDD:197706	3/8 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23279
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100