DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr3 and LOC101885129

DIOPT Version :9

Sequence 1:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	XP_021333804.1	Gene:	LOC101885129 / 101885129	-ID:	-	Length:	654	Species:	Danio rerio

Alignment Length:	389	Identity:	77/389 - (19%)
Similarity:	110/389 - (28%)	Gaps:	163/389 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 TLSTFLSSSQSQSPSPPAASASASSPSSFSSFAVAHGPQTE-ATNHTFKSLAFLDASFGSDLFAQ 211
            |.:||:..             ||::|||.|     |...|: :..||           ||
Zfish     5 TTNTFIDK-------------SAATPSSLS-----HPNNTKLSVPHT-----------GS----- 35

  Fly   212 TDAKRERSGAADEESQDADTSQSLPIFDFGMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIR--- 273
                          |:..||...|.|...|...|.|           |.:.:....||.||:
Zfish    36 --------------SETTDTQNYLKIVQAGDTVNFT-----------CSLSNEIRSSVVWIKQSV 75

  Fly   274 -KRDLHILTVGTAT-------YTSDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQVNTEPKMS 330
             |:.|.:::.....       :....||.||  ||...:.|.:......||..|.|       ::
Zfish    76 GKKPLPVVSSFQIVDHRFENDFNKQNRFFVT--KDDVSFNLSITNTEVSDSATYYC-------IT 131

  Fly   331 MAFQLNIIEISPDAKAVISGPPDLHFKAGSAII---------------LNCLVQQPSVKDIGPIY 380
            .|:..           ......||..|||...|               |.|.:...|..:...:|
Zfish   132 YAYHF-----------TFGNSTDLIVKAGGVNIESEHERSASESPSEDLQCSIISQSCAEEHRVY 185

  Fly   381 WYRGEHMITPFDADDGQPEIPAGRGEHPQGI----------------PEDTSPNDIMS----EVD 425
            |:|..                  .||.|.|:                |..|:...|.|    :.|
Zfish   186 WFRQR------------------SGESPPGVIYTQDSRSAQCENSSDPNSTAHKCIYSLPKTDED 232

  Fly   426 LQMEFATRIAMESQL--GDTLKSRLR----------------ISNAQTTDTGNYTCQPTTASSA 471
            ..:.:.. :|...|:  ||..|..||                |.:....|:.|..|...|.|.|
Zfish   233 PAIYYCA-VAACGQILFGDGRKFCLRGPDSATDRNTTLHQSLIDSVDPGDSVNLQCSIFTESCA 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	20/97 (21%)
		IG_like	243..329	CDD:214653	20/96 (21%)
		Ig	350..464	CDD:299845	31/166 (19%)
		IG_like	<441..477	CDD:214653	12/47 (26%)
LOC101885129	XP_021333804.1	Ig	47..146	CDD:325142	25/129 (19%)
		Ig	161..253	CDD:325142	19/110 (17%)
		V-set	354..454	CDD:311561
		V-set	470..566	CDD:311561
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1457433at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010