DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33543 and KIRREL2

DIOPT Version :9

Sequence 1:NP_001014458.3 Gene:CG33543 / 3346207 FlyBaseID:FBgn0053543 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_954649.3 Gene:KIRREL2 / 84063 HGNCID:18816 Length:708 Species:Homo sapiens


Alignment Length:327 Identity:73/327 - (22%)
Similarity:108/327 - (33%) Gaps:102/327 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 PPTPPLSLQPSTPSITHFVNESFIIFCQTVQKDIDTKWRDPRGQTRE-NTKG-RVHIEKKTTGLL 105
            ||...||..|.|..    ..|..|..||...:...|.:|..:|.:.. ..:| |:.:....:.|.
Human   226 PPEVTLSASPHTVQ----EGEKVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADASFLT 286

  Fly   106 ALVFEHIALEDRGNWTCEV-NGNRNGNRNVNVEREFLASFELLVNQKISFG-----KTEQVQSVR 164
            ..|            :||| |...:.||:..::              :.||     |.|.| ||.
Human   287 EPV------------SCEVSNAVGSANRSTALD--------------VLFGPILQAKPEPV-SVD 324

  Fly   165 EGRDAMVNCFVEGMPAPEVSWLYNGEYINTVNSTKHNRLSNGLYIR--NVSQADAGEYTCRA--- 224
            .|.||..:|...|.|.|.|:|...|         ....|.:|..:|  :|...|||:|.|||   
Human   325 VGEDASFSCAWRGNPLPRVTWTRRG---------GAQVLGSGATLRLPSVGPEDAGDYVCRAEAG 380

  Fly   225 ----------MRITPTFSDSDQITILLRIQHKPHWFFNETLPVQYAYVGGAVNLSCDAMGEPPPS 279
                      .|:|     .:...::..:...|            |::.|...|.|.....|.|.
Human   381 LSGLRGGAAEARLT-----VNAPPVVTALHSAP------------AFLRGPARLQCLVFASPAPD 428

  Fly   280 ---FTWLHNNKGIV--GFNHRIFVADYGA-------------TLQLQMKNASQFG-DYKCKVANP 325
               ::|   ::|.:  |...|..|..:.|             .|.:.....|.|. .:.|...|.
Human   429 AVVWSW---DEGFLEAGSQGRFLVETFPAPESRGGLGPGLISVLHISGTQESDFSRSFNCSARNR 490

  Fly   326 LG 327
            ||
Human   491 LG 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33543NP_001014458.3 IGc2 165..224 CDD:197706 19/60 (32%)
IG_like 256..336 CDD:214653 19/91 (21%)
IGc2 263..327 CDD:197706 16/82 (20%)
FN3 341..445 CDD:238020
KIRREL2NP_954649.3 IG_like 30..119 CDD:214653
IGc2 38..106 CDD:197706
I-set 126..224 CDD:254352
Ig2_KIRREL3-like 141..223 CDD:143236
Cell attachment site. /evidence=ECO:0000255 149..151
Ig 231..306 CDD:299845 21/90 (23%)
IG_like 234..308 CDD:214653 19/103 (18%)
Ig 312..395 CDD:299845 28/97 (29%)
I-set 317..395 CDD:254352 28/92 (30%)
Ig 397..501 CDD:299845 20/111 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 545..601
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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