DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and DIP-delta

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001097508.2	Gene:	DIP-delta / 5740816	FlyBaseID:	FBgn0085420	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	75/304 - (24%)
Similarity:	125/304 - (41%)	Gaps:	42/304 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 EDRGNWTCEVNGN----RNGNRNVNVEREFLASFELLVNQKISFGKTEQVQSVREGRDAMVNCFV 175
            :|||.:.|:||.|    :.|...|.|....|           ....|....:|||.::..:.|..
  Fly   118 DDRGYYMCQVNTNPMISQVGYLQVVVPPNIL-----------DIESTPSSVAVRENQNINMTCRA 171

  Fly   176 EGMPAPEVSW-LYNGEYINTVNSTKHNRL--SNGLYIRNVSQADAGEYTCRAMR-ITPTFSDSDQ 236
            :|.|||::.| ..:||.| .|...|...:  ::.|.:..||:.:.|.|.|.|.. :.|:.|.
  Fly   172 DGFPAPKIIWRREDGEEI-AVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSVSK--- 232

  Fly   237 ITILLRIQHKPH-WFFNETLPVQYAYVGGAVNLSCDAMGEPPPSFTWLHNNKGIVGFNHRIFVAD 300
             .|:|.::..|. |..|:.:.   |..|..|.:.|.....|.....|::|:  ::....:.:..|
  Fly   233 -RIILDVEFSPMIWVPNQLVG---APSGTDVTIDCHTEAHPKAIIYWVYNS--VMVLPSKKYKTD 291

  Fly   301 -----YGATLQLQMKNA--SQFGDYKCKVANPLGMLERVIKLRPGPKPLGPRRFQLKKLYTNGFE 358
                 |.|.::|.::|.  ..||:|:|...|.||..|..|::...|.|..|.: |:........|
  Fly   292 YTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLPSTPSK-QVTHTTVESRE 355

  Fly   359 LDIQTPRMSNVSDEMQI-YGYRV---AYMSDTEFKFSAGNWSYA 398
            .:|.....::.:..:|. .||.:   .|........|.|:.|.|
  Fly   356 NNIIPSSRNDTTKSLQTDVGYAMKNDLYPGSASSSSSGGSSSAA 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	18/61 (30%)
		IG_like	256..336	CDD:214653	21/86 (24%)
		IGc2	263..327	CDD:197706	16/70 (23%)
		FN3	341..445	CDD:238020	13/62 (21%)
DIP-delta	NP_001097508.2	IG	51..143	CDD:214652	9/24 (38%)
		Ig	145..238	CDD:416386	27/108 (25%)
		Ig strand A	145..149	CDD:409353	1/14 (7%)
		Ig strand A'	154..159	CDD:409353	0/4 (0%)
		Ig strand B	165..172	CDD:409353	1/6 (17%)
		Ig strand C	178..183	CDD:409353	1/4 (25%)
		Ig strand C'	185..187	CDD:409353	0/1 (0%)
		Ig strand D	195..199	CDD:409353	1/3 (33%)
		Ig strand E	203..209	CDD:409353	1/5 (20%)
		Ig strand F	216..223	CDD:409353	3/6 (50%)
		Ig strand G	230..238	CDD:409353	3/11 (27%)
		Ig	242..333	CDD:416386	24/95 (25%)
		Ig strand A'	250..253	CDD:409353	0/5 (0%)
		Ig strand B	259..266	CDD:409353	2/6 (33%)
		Ig strand C	272..277	CDD:409353	1/4 (25%)
		Ig strand C'	281..283	CDD:409353	0/1 (0%)
		Ig strand D	289..293	CDD:409353	1/3 (33%)
		Ig strand E	295..305	CDD:409353	3/9 (33%)
		Ig strand F	314..322	CDD:409353	3/7 (43%)
		Ig strand G	325..334	CDD:409353	3/8 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000