DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and dscama

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	332	Identity:	82/332 - (24%)
Similarity:	129/332 - (38%)	Gaps:	58/332 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 ELLVNQKISFGKTEQVQSVREGRDAMVNCFVEGMPAPEVSWLYNG-------EYINTVNSTKHNR 202
            :|:|.....|....|.|....|:..::||..:|.|.|.:.|.|:.       :.|...:..:...
Zfish   684 QLIVRVPPRFKVQPQDQDGIYGKSVILNCSADGEPRPTIEWKYSKGAGVPQFQPIALNSGFRVQL 748

  Fly   203 LSNG-LYIRNVSQADAGEYTCRAMR-ITPTFSDSDQITILL--RIQHKPHWFFNETLPVQYAYVG 263
            |.|| |.|::|.:.|||.|.|:... :....|.|..:.:.:  .|...|    |.:|    |..|
Zfish   749 LGNGSLLIKHVLEEDAGYYLCKVSNDVGADVSKSMYLNVKIPAMITSYP----NNSL----ATKG 805

  Fly   264 GAVNLSCDAMGEPPPSFTW---LHNNKGIVGFN-----HRIFVADYG----ATLQLQMKNASQFG 316
            ..:.:||.|.||.|....|   :...|.....|     |.:.|.:.|    :|||:........|
Zfish   806 EKIEMSCKAHGEKPIMVRWEKEVEKEKQSHMINPDMWRHTVTVKNVGDEVVSTLQIYPTMREDSG 870

  Fly   317 DYKCKVANPL----GMLERVIKLRPGPKPLGPRRFQLKKL---YTNGFELDIQTPRMSNVSDEMQ 374
            .:.|...|..    |:|:..::..|.|..:..|..:.:.:   :|.||:            ....
Zfish   871 FFSCHAINSYGEDRGILQLTVQEPPEPPKVEIREVKERTIALRWTMGFD------------GNSL 923

  Fly   375 IYGYRVAYMSDTEFKFSAGNWSYAKQ-RDFSFHGGKHFIIPHLETNTTYLMRAASRNLAGLSDWS 438
            |.||      |.|.|.....|..|:: ||.|....:..|| .|..::||.:|..::|..|.|:.|
Zfish   924 ITGY------DIECKNKTETWERARRTRDVSPTLNQATII-ELHPSSTYNIRMFAKNHIGDSEPS 981

  Fly   439 PVKVFTT 445
            .....||
Zfish   982 NELTVTT 988

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	20/66 (30%)
		IG_like	256..336	CDD:214653	22/95 (23%)
		IGc2	263..327	CDD:197706	19/79 (24%)
		FN3	341..445	CDD:238020	25/107 (23%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352
		IG_like	321..402	CDD:214653
		I-set	408..502	CDD:333254
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211	21/78 (27%)
		Ig	805..898	CDD:325142	22/92 (24%)
		FN3	894..988	CDD:238020	27/112 (24%)
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900