DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and paplna

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	311	Identity:	71/311 - (22%)
Similarity:	124/311 - (39%)	Gaps:	73/311 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LSLQPSTPS-ITHFVNESFIIFCQTV---QKDIDTKWR------DPRGQTRENTKGRVHIEKKTT 102
            :|:..:.|| :...|.:..::.|:..   ...:..:||      ||   ||.        |::..
Zfish   832 VSIDKTDPSTVEGLVGQRVVLPCRVTPPPSSAVLVEWRRDGVPVDP---TRH--------EQQLD 885

  Fly   103 GLLALVFEHIALEDRGNWTC---------------EVNGNRNGNRNVNVEREFLASFELLVNQKI 152
            |  :|:...|.|:|.|.:.|               .|:|:...|..:: |.:...|:....:.:.
Zfish   886 G--SLLVGPITLQDSGWFLCVATRDDKRDHRYIYLSVSGSSQNNAGIS-EVDSSQSYTSQSSSRF 947

  Fly   153 SFGKTEQVQSVREGRDAMVNCF---VEGMPAPEVSWLYNGEYINTVNSTKHNRLSNG-LYIRNVS 213
            :...:..|:: |.|:.|.:.|.   |..:.|..:.|...|:   .:||.:|::.|:| |.|:.::
Zfish   948 NIDYSPLVEA-RAGQTAKLQCSVLPVSAIHAVTIHWSRAGQ---PLNSLRHSQHSDGTLVIKQLT 1008

  Fly   214 QADAGEYTCRAMRITPTFSDSD-------QITIL--LRIQHKPHWFFNETLPVQYAYVGGAVNLS 269
            ..|:|.|||       |.:|:.       |:.:|  |||...|       :.|.... |....|:
Zfish  1009 ADDSGLYTC-------TVTDAQKFEERQVQLRVLGDLRITKAP-------IDVDVVQ-GSTAQLA 1058

  Fly   270 CDAMGEPPPSFTWLHNNKGIVGFNHRIFVADYGATLQLQMKNASQFGDYKC 320
            |...|| ..:..|..|...:....||:.|:..| ||.|....:...|.|.|
Zfish  1059 CVVTGE-NVNVGWSRNGVPVRPDGHRVHVSADG-TLILNNVQSVDEGTYTC 1107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	19/62 (31%)
		IG_like	256..336	CDD:214653	18/65 (28%)
		IGc2	263..327	CDD:197706	17/58 (29%)
		FN3	341..445	CDD:238020
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449	18/79 (23%)
		IGc2	960..1022	CDD:197706	20/71 (28%)
		I-set	1039..1121	CDD:333254	21/79 (27%)
		PLAC	1142..1173	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900