DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and dpr6

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	66/343 - (19%)
Similarity:	116/343 - (33%)	Gaps:	115/343 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IALCSLLLLLLSQNAAILGQLDSTSSGGSG----------------TGGAPPDRPPTPPLS---- 49
            :.||...||||    .::...|.|:.|..|                |.|......||.|.:
  Fly     7 LPLCVAWLLLL----VVIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTAPTAAYTH 67

  Fly    50 -------LQPSTP-SITHFVNESFIIFCQTVQKDIDTK---W---RDPRGQTRENTKGRVHIEKK 100
                   ..|||| ::|..:.:|..:.|:.  :::..|   |   ||            :||  .
  Fly    68 PKWMEPYFDPSTPRNVTALMGKSAYLSCRV--RNLANKTVSWIRHRD------------IHI--L 116

  Fly   101 TTGLLALV----FEHIALEDRGNWTCEVN-------GNRNGNRNVNVEREFLASFELLVNQKISF 154
            |.|.....    |:....:|..:||.::.       |......:....|.:.....::|......
  Fly   117 TVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATIL 181

  Fly   155 GKTEQVQSVREGRDAMVNCFVEGMPAPE--VSWLYNGEYIN--------TVNSTKHNRLSNGLYI 209
            |..:  ..|.:|....:.|.|:..|.|.  :.|.::.|.||        :|.:.|.:..::.|.|
  Fly   182 GGPD--LHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLI 244

  Fly   210 RNVSQADAGEYTCRAMRITPTFSDSDQITILLRIQHKPHWFFNETLPVQYAYVGGAVNLSCDAMG 274
            :|...||:|:|:|..       |::|..::.:.:                      :|:.....|
  Fly   245 QNADLADSGKYSCAP-------SNADVASVRVHV----------------------LNVRAIISG 280

  Fly   275 EPPPS---------FTWL 283
            |.|.:         :.||
  Fly   281 EHPEAMQTGSSGCQYNWL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	19/68 (28%)
		IG_like	256..336	CDD:214653	6/37 (16%)
		IGc2	263..327	CDD:197706	6/30 (20%)
		FN3	341..445	CDD:238020
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	19/110 (17%)
		IG_like	80..175	CDD:214653	18/110 (16%)
		IG_like	184..271	CDD:214653	22/95 (23%)
		IGc2	191..262	CDD:197706	20/77 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810