back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33543 and OPCML

DIOPT Version :10

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001306032.1	Gene:	OPCML / 4978	HGNCID:	8143	Length:	354	Species:	Homo sapiens

Alignment Length:	320	Identity:	66/320 - (20%)
Similarity:	110/320 - (34%)	Gaps:	99/320 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 FVNESFIIFCQTVQKDIDTKWR-DPRGQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCE 123
            ::|.|.|::..      :.||. ||          ||.|...|....:::.:::.:.|.|.:||.
Human    68 WLNRSTILYAG------NDKWSIDP----------RVIILVNTPTQYSIMIQNVDVYDEGPYTCS 116

  Fly   124 VNGNRNGNRN-----VNVEREFL-ASFELLVNQKISFGKTEQVQSVREGRDAMVNCFVEGMPAPE 182
            |..:.:...:     |.|..:.: .|.::.||               ||....:.|...|.|.|.
Human   117 VQTDNHPKTSRVHLIVQVPPQIMNISSDITVN---------------EGSSVTLLCLAIGRPEPT 166

  Fly   183 VSWLYNGEYINTVNSTKHNRLSNG---------LYIRNVSQADAGEYTCRAMRITPTFSDSDQIT 238
            |:|             :|..:..|         |.|.::.:..:|||.|.|:.   ..:..|...
Human   167 VTW-------------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN---DVAAPDVRK 215

  Fly   239 ILLRIQHKPHWFFNETLPVQYAYVGGAVN----------LSCDAMGEPPPSFTWLHNN----KGI 289
            :.:.:.:.|             |:..|.|          |||:|...|...|.|....    .|:
Human   216 VKITVNYPP-------------YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267

  Fly   290 VGFNHRIFVADYGATLQLQMKNASQ--FGDYKCKVANPLGMLERVI---KLRPGPKPLGP 344
            .|..    :.:.|....|...|.|:  :|:|.|...|.||.....|   ::.|.....||
Human   268 DGMR----IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEISPSSAVAGP 323

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.