DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33543 and opcml

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	304	Identity:	68/304 - (22%)
Similarity:	111/304 - (36%)	Gaps:	82/304 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 FVNESFIIFCQTVQKDIDTKWR-DPRGQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCE 123
            ::|.:.|:|..      :.||. ||          ||.:........::...::.|.|.|.:.|.
Zfish    65 WLNRTTILFTG------NEKWSLDP----------RVVLLNTAVNEYSIKILNVNLYDEGPYVCS 113

  Fly   124 VNGNRNGN------------RNVNVEREFLASFELLVNQKISFGKTEQVQSVREGRDAMVNCFVE 176
            :..|:...            |.|||..:.                     ||.||.:..:.|...
Zfish   114 ILTNKKPESTKVHLIVQVPARIVNVSTDV---------------------SVNEGSNVSLMCLAI 157

  Fly   177 GMPAPEVSWLYNGEYINTVNSTKHNRL-SNGLYIR--NVSQADAGEYTCRAMRITPT-FSDSDQI 237
            |.|.|.:.|.:        .|:|.||: :.|.|:.  .:::..:|.|.|    ||.. .|..|..
Zfish   158 GRPEPSILWKF--------RSSKGNRIVTEGEYVEMTGITKDMSGSYDC----ITSNDISPPDVR 210

  Fly   238 TILLRIQHKPHWFFNETLPVQYAYVGGAVN----LSCDAMGEPPPSFTWLHNNKGIV-GFNHRIF 297
            |:.:.:.:.|       :..:....|.||.    |.|:|...|...|.|....:.|: ||| .:.
Zfish   211 TVQVTVNYPP-------VISRARSTGTAVGQKGVLWCEASAVPLADFQWFKGERRILNGFN-GVK 267

  Fly   298 VADYGATLQLQMKNASQ--FGDYKCKVANPLGMLE-RVIKLRPG 338
            :.:.|....|...|.|:  :|:|.|...|.||:.. .:|...||
Zfish   268 IENKGKQSMLTFFNVSEEDYGNYTCVAINTLGITNASIILYGPG 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	16/61 (26%)
		IG_like	256..336	CDD:214653	24/87 (28%)
		IGc2	263..327	CDD:197706	21/70 (30%)
		FN3	341..445	CDD:238020
opcml	NP_001005580.1	Ig	41..129	CDD:299845	14/79 (18%)
		IG_like	41..129	CDD:214653	14/79 (18%)
		IG_like	139..216	CDD:214653	23/109 (21%)
		IGc2	146..202	CDD:197706	18/67 (27%)
		I-set	219..307	CDD:254352	24/95 (25%)
		ig	223..307	CDD:278476	23/84 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576325
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.790