DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and ImpL2

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	58/278 - (20%)
Similarity:	102/278 - (36%)	Gaps:	68/278 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LCSLLLLLLSQNAAILGQ---LDSTSSGGSGTGGAPPDRP-------------PTPPLSLQPSTP 55
            :|:|.|||....|.:.|:   |...|:....:..|..::|             .|||..||.:..
  Fly     9 VCALALLLFGSIATVRGRAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADG 73

  Fly    56 SITHFVNESFIIFCQTVQKDIDT-KW---RDPRGQTRENTKGRVHIEKKTTGLLAL----VFEHI 112
            :....|       |:.:...:.: :|   ..||.:..:....:| .|:..:.::.:    :.:|:
  Fly    74 ATIEIV-------CEMMGSQVPSIQWVVGHLPRSELDDLDSNQV-AEEAPSAIVRVRSSHIIDHV 130

  Fly   113 ALEDRGNWTCEVNGNRNGNRNV--------------NVEREFLASFELLVNQKISFGKTEQVQSV 163
            ..|.| .:||.   .|.|::.:              ..|:.:..:      ||.....||:....
  Fly   131 LSEAR-TYTCV---GRTGSKTIYASTVVHPPRSSRLTPEKTYPGA------QKPRIIYTEKTHLD 185

  Fly   164 REGRDAMVNCFVEGMPAPEVSWLYNGEYINTVNSTKHNRLSNG-LYIRNVSQADAGEYTCRAMRI 227
            ..|.:..:.|.|...|..|::|| |.|....|...:|..|:|| |.|..:...|.|.|.|.|..:
  Fly   186 LMGSNIQLPCRVHARPRAEITWL-NNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNV 249

  Fly   228 T----------PTFSDSD 235
            .          |..::.|
  Fly   250 VGKDTADTFVYPVLNEED 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	20/59 (34%)
		IG_like	256..336	CDD:214653
		IGc2	263..327	CDD:197706
		FN3	341..445	CDD:238020
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	21/64 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900