DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and dpr20

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	62/341 - (18%)
Similarity:	114/341 - (33%)	Gaps:	86/341 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 NAAILGQLDSTSSGGSGTGGAPPDRPPTPPLSLQPSTPSITHFVNESFIIFCQTVQKDIDTKWRD 82
            ||.:...:.:||||...:..|....|      .:|:....|..|..|.:        .:|:|...
  Fly   182 NALVPATVATTSSGLPSSSNASLATP------TEPARNRSTGLVRNSAV--------KVDSKHPL 232

  Fly    83 PRGQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCEVNGNRNGNRNVNVEREFLASFELL 147
            .:||            |....:|..:|:..:               :.|::.:.::.:...||.:
  Fly   233 SKGQ------------KTDAPMLNYIFDTFS---------------SANKHHHHDQRYGPHFEDV 270

  Fly   148 VNQKISFGKTEQVQSVREGRDAMVNCFVEGMPAPEVSWLY---------NGEYINTVNSTKHNRL 203
              |:|  |:...: :|:.|....:||.:..:....|||:.         ||..::.:....|...
  Fly   271 --QRI--GQATNL-TVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYT 330

  Fly   204 SNGLY-------------IRNVSQADAGEYTCRAMRITPTFSDSDQITILLRIQHKPHWFFNET- 254
            .:..|             |.||.:.|...|.|:.....|..     |.|.|.:........:|.
  Fly   331 GDKRYKMEFQYPNNWRLKITNVKKDDEAIYECQISTHPPRV-----IQINLHVNAPKVMIVDEVG 390

  Fly   255 --LPVQYAYVGGAVNLSCDAMGEPPPSFT--WLHNN--------KGIVGFNHRIFVADYGATLQL 307
              |..:|..:...:.|||........|..  |.|.:        :|.|.....:......:||.:
  Fly   391 DPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSI 455

  Fly   308 QMKNASQFGDYKCKVA 323
            ...:.:..|:|.|.::
  Fly   456 AKISKTDSGNYTCSIS 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	16/80 (20%)
		IG_like	256..336	CDD:214653	14/78 (18%)
		IGc2	263..327	CDD:197706	13/71 (18%)
		FN3	341..445	CDD:238020
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	17/87 (20%)
		Ig	279..378	CDD:299845	21/104 (20%)
		Ig	400..471	CDD:299845	13/70 (19%)
		IG_like	402..480	CDD:214653	13/70 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900