DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and wrapper

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	99/505 - (19%)
Similarity:	177/505 - (35%)	Gaps:	144/505 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LCSLLLLLLSQNAAILGQLDSTSSGGSGTGGAPPDRP-PTPPLSLQPSTPSITHFVNESFIIFCQ 70
            :||::..||:  |.||||:.:.....:....:...:. ||...:.:..|..:...:|..| .:.:
  Fly     5 MCSVVRCLLA--ALILGQVQAELDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPF-RYVR 66

  Fly    71 TVQKD---IDTK------------WRDPRGQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNW 120
            ..:.|   :|::            |  |.|                    :|...::...|.|::
  Fly    67 WHRDDVALVDSRHPELPPPDRIMLW--PNG--------------------SLQVANVQSSDTGDY 109

  Fly   121 TCEVNGNRNGNRNVNVEREFLASFELLVNQKIS-FGKTEQVQSVREGRDAMVNCFVEGMPAPEVS 184
            .||:|.:..     :|.::.....:|.....|. ...|||    |.|....|.|..:|:|.|.::
  Fly   110 YCEMNSDSG-----HVVQQHAIEVQLAPQVLIEPSDLTEQ----RIGAIFEVVCEAQGVPQPVIT 165

  Fly   185 WLYNGEYINTVNSTKHNRLSNGLYIRNVSQADAGEYTCRAMRITPTFSDSDQITILLRIQHKPHW 249
            |..||..|...::| .||.|..|.|::.:|  ||...|.|   :....:.....:.|.:...|..
  Fly   166 WRLNGNVIQPQSNT-GNRQSLILEIKSRNQ--AGLIECVA---SNGVGEPAVANVYLHVLFSPEV 224

  Fly   250 FFNETLPVQYAYVGGAVNLSCDAMGEPPPSFTWLHN-------------------NKGIVGFNHR 295
            ...:  ||.|..:|...:|.|.....|..:..|.|:                   |:.:   :|.
  Fly   225 SIPQ--PVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSV---DHY 284

  Fly   296 IFVADYGATLQLQMKNASQFGDYKCKVANPLGMLERVIKLRPGPKP----LGPRR---------F 347
            :....:...:: .::|| ..|.|:|:.:|.:.:....::|...|.|    :.|..         :
  Fly   285 VNAVRHMLVVK-SVRNA-DMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQSSTSHVLVW 347

  Fly   348 QLKKLY-TNGFELDIQTPRMSNVSDEMQIYGYRVAYMSDTEFKFSAGNWSYAKQRDFSFHGGKHF 411
            |.:.|. ...|:|..:....:||:.:::.                  ||:             ..
  Fly   348 QTESLLPIMEFKLKFRQIPSNNVTRQVRT------------------NWT-------------EL 381

  Fly   412 IIPHLETN-----TTYLMR-----------AASRNLAGLSDWSPVKVFTT 445
            .||...||     |||.:.           ..:||..|.||.|.:..|.|
  Fly   382 TIPAQATNGLIYITTYTLHGLQPASLYEVSVLARNSFGWSDNSKIVRFAT 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	20/58 (34%)
		IG_like	256..336	CDD:214653	17/98 (17%)
		IGc2	263..327	CDD:197706	14/82 (17%)
		FN3	341..445	CDD:238020	24/133 (18%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	17/110 (15%)
		IG_like	41..118	CDD:214653	16/99 (16%)
		IG_like	145..218	CDD:214653	23/78 (29%)
		Ig	147..219	CDD:299845	22/77 (29%)
		I-set	224..323	CDD:254352	17/105 (16%)
		IGc2	236..314	CDD:197706	14/82 (17%)
		FN3	339..431	CDD:238020	22/122 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900