DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and dpr3

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	68/353 - (19%)
Similarity:	104/353 - (29%)	Gaps:	135/353 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LSQNAAILGQLDSTSSG---GSGTGGAPPDRPPTPPLSLQPSTPS------ITH----------- 59
            |:..||..||.|.:..|   .:....:....|..|..|...|:||      :.|
  Fly   130 LAAAAASTGQPDDSGDGPTLSTFLSSSQSQSPSPPAASASASSPSSFSSFAVAHGPQTEATNHTF 194

  Fly    60 ----FVNESF--IIFCQTVQK------------DIDTKWRDP-------------RGQTRENTKG 93
                |::.||  .:|.||..|            |.||....|             .|.|....|.
  Fly   195 KSLAFLDASFGSDLFAQTDAKRERSGAADEESQDADTSQSLPIFDFGMPRNITGRTGHTEAIIKC 259

  Fly    94 RVH---------IEKKTTGLLAL---------VFEHIALEDRGNWTCEVN---GNRNG--NRNVN 135
            ||.         |.|:...:|.:         .|:....:|...||..|.   ...:|  ...||
  Fly   260 RVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQVN 324

  Fly   136 VEREFLASFELLVNQKISFGKTEQVQS-----VREGRDAMVNCFVEGMPAPEVS---WLYNGEYI 192
            .|.:...:|:|.:.: ||......:..     .:.|...::||.|:.....::.   | |.||::
  Fly   325 TEPKMSMAFQLNIIE-ISPDAKAVISGPPDLHFKAGSAIILNCLVQQPSVKDIGPIYW-YRGEHM 387

  Fly   193 NT----------------------------------------------VNSTKHNRLSNGLYIRN 211
            .|                                              :.|...:.|.:.|.|.|
  Fly   388 ITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQLGDTLKSRLRISN 452

  Fly   212 VSQADAGEYTCRAMRITPTFSDSDQITI 239
            ....|.|.|||:     ||.:.|..:.:
  Fly   453 AQTTDTGNYTCQ-----PTTASSASVLV 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	19/107 (18%)
		IG_like	256..336	CDD:214653
		IGc2	263..327	CDD:197706
		FN3	341..445	CDD:238020
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	17/86 (20%)
		IG_like	243..329	CDD:214653	17/85 (20%)
		Ig	350..464	CDD:299845	18/114 (16%)
		IG_like	<441..477	CDD:214653	12/40 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900