DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33543 and Kirrel1

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_006232737.1	Gene:	Kirrel1 / 310695	RGDID:	727883	Length:	805	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	82/331 - (24%)
Similarity:	118/331 - (35%)	Gaps:	87/331 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PPTPPLSLQPSTPSITHFVNESFIIFCQ-TVQKDI-DTKWRDPRGQTRENTKGRVHIEK------ 99
            |||..||::|.|.    ...|..|..|| |...:| ..:|          .||...||.
  Rat   254 PPTVTLSIEPQTV----LEGERVIFTCQATANPEILGYRW----------AKGGFLIEDAHESRY 304

  Fly   100 KTTGLLALVFEHIALEDRGNWTCEVNGNRNGNRNVNVEREFLASFELLVNQKISFGKTEQV---- 160
            :|....:...|.:        :|||. |:.|:.||:.          |||  :.|.....|
  Rat   305 ETNVDYSFFTEPV--------SCEVY-NKVGSTNVST----------LVN--VHFAPRIVVYPKP 348

  Fly   161 QSVREGRDAMVNCFVEGMPAPEVSWLYNGEYINTVNSTKHNRL----------------SNGLYI 209
            .:...|.|..:.|...|.|...::|       ...:|....||                ||.|.:
  Rat   349 TTTDIGSDVTLTCVWVGNPPLTLTW-------TKKDSNMGPRLPGSPPEANLSAQVLSNSNQLLL 406

  Fly   210 RNVSQADAGEYTCRAMRITPTFSDSDQITILLRIQHKPHWFFNETLPVQYAYVGGAVNLSCDAMG 274
            ::|:|||||.|||||  |.|....::: .:.|.:...|   ...:..||:|..|....:.|....
  Rat   407 KSVTQADAGTYTCRA--IVPRIGVAER-EVPLYVNGPP---IISSEAVQFAVRGDGGKVECFIGS 465

  Fly   275 EPPP---SFTWLHNNKGIVGFNHRIFV----ADYGATLQLQMKNASQFG---DYKCKVANPLGML 329
            .|||   ::.|..|... ||...|..|    :..|....|.:.|..:..   .|.|...|..|..
  Rat   466 TPPPDRIAWAWKENFLE-VGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPG 529

  Fly   330 ERVIKL 335
            ..:|:|
  Rat   530 TAIIQL 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	21/74 (28%)
		IG_like	256..336	CDD:214653	23/90 (26%)
		IGc2	263..327	CDD:197706	17/73 (23%)
		FN3	341..445	CDD:238020
Kirrel1	XP_006232737.1	I-set	54..148	CDD:254352
		Ig	57..148	CDD:299845
		Ig2_KIRREL3-like	170..251	CDD:143236
		I-set	255..336	CDD:254352	29/115 (25%)
		Ig_2	259..337	CDD:290606	27/112 (24%)
		Ig_2	340..437	CDD:290606	27/106 (25%)
		IG_like	346..437	CDD:214653	26/100 (26%)
		Ig5_KIRREL3	439..536	CDD:143306	24/101 (24%)
		IG_like	451..536	CDD:214653	21/86 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900