Protein Alignment CG33543 and Igsf9

DIOPT Version :10

• Sequence 1: NP_001014458.3
• Gene: CG33543 / 3346207
• FlyBaseID: FBgn0053543
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001100667.1
• Gene: Igsf9 / 304982
• RGDID: 1304566
• Length: 1179
• Species: Rattus norvegicus
• Alignment Length: 557
• Identity: 103/557 - (18%)
• Similarity: 169/557 - (30%)
• Gaps: 185/557 - (33%)

  Fly    35 TGGAPPDRPPTPPLSLQPSTPSITHFVNESFIIFCQTV---QKDIDTKWRDPRGQTRENTKGRVH 96
            |..:||....||||.|:...       .|:..:.|..:   |..:..|:   |||.....:|:|.
  Rat   131 TVNSPPQFQETPPLVLEVKE-------LEAVTLRCVALGSPQPYVTWKF---RGQDLGKGQGQVQ 185

  Fly    97 IEKKTTGLLALVFEHIALEDRGNWTCEVNGNRNGNRNVNVEREFLASFELLVNQKISFGKTEQVQ 161
            :...|     |....:.....|::||:.:         :.|.....:.:|||.............
  Rat   186 VRNGT-----LWIRRVERGSAGDYTCQAS---------STEGSVTHTTQLLVLGPPVIVVPPNNN 236

  Fly   162 SVREGRDAMVNCFVEGMPAP-EVSWL---YNGEYINTVNSTKHNRLSNGLYIRNVSQADAGEYTC 222
            :|...:|..:.|..|..||. ..||.   .|..:|:.:.|.....:...|:::.....|||.|||
  Rat   237 TVNASQDVSLACRAEAYPANLTYSWFQDRINVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTC 301

  Fly   223 RAMRITP---------TFSDSDQITIL-----------------------------------LRI 243
            ......|         |.....|:|::                                   |::
  Rat   302 VPSNGFPHPPSASAYLTVLYPAQVTVMPPETPLPIGMRGVIRCPVRANPPLLFVTWTKDGQALQL 366

  Fly   244 QHKPHW-----------------------------------------------FFNETLPVQYAY 261
            ...|.|                                               |.::.....:..
  Rat   367 DKFPGWSLGPEGSLVIALGNEDALGEYSCTPYNSLGTAGSSPVTRVLLKAPPAFIDQPKEEYFQE 431

  Fly   262 VGGAVNLSCDAMGEPPPSFTWLHNNKGIVGFNHRIFVADYGATLQLQMKNASQFGDYKCKVANPL 326
            ||..:.:.|.|.|:|||..:|....:|:.|...    .|...:|.|:.......|.::|...|.:
  Rat   432 VGRDLLIPCSARGDPPPIVSWAKVGRGLQGQAQ----VDSNNSLILRPLTKEAHGRWECSARNAV 492

  Fly   327 GMLERVIKLRPGPKPLGPRRFQLKKLYTNGFELD-----------IQTPRMSNVSDEMQIYGYRV 380
            ..:                     .:.||.:.|.           :..|:.:|||.|.   |:..
  Rat   493 AHV---------------------TISTNVYVLGTSPHVVTNVSVVPLPKGANVSWEP---GFDG 533

  Fly   381 AYMSDTEFKFSAGNWSYAKQRDFSFH---------GGKHFIIPHLETNTTYLMRAASRNLAGLSD 436
            .|:.    :||......||:.|.:.|         |..|.::|.|:..|.|.....::|..|...
  Rat   534 GYLQ----RFSVWYTPLAKRPDRAHHDWVSLAVPMGATHLLVPGLQAYTQYQFSVLAQNKLGSGP 594

  Fly   437 WS------PVKVFTTAA-----GCSWSPWLYPSYGLI 462
            :|      |..:.||.|     .....|.|.|..||:
  Rat   595 FSEIVLSIPEGLPTTPAVPRLPPTEMPPPLSPPRGLV 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	Ig	<71..>123	CDD:472250	11/54 (20%)
		Ig strand E	105..109	CDD:409353	1/3 (33%)
		Ig strand F	119..123	CDD:409353	1/3 (33%)
		Ig	153..239	CDD:472250	21/98 (21%)
		Ig strand B	169..173	CDD:409353	0/3 (0%)
		Ig strand C	182..186	CDD:409353	1/3 (33%)
		Ig strand E	205..209	CDD:409353	1/3 (33%)
		Ig strand F	219..224	CDD:409353	3/4 (75%)
		Ig strand G	232..235	CDD:409353	0/2 (0%)
		IG_like	256..336	CDD:214653	17/79 (22%)
		Ig strand B	266..270	CDD:409353	0/3 (0%)
		Ig strand C	279..283	CDD:409353	0/3 (0%)
		Ig strand E	302..309	CDD:409353	2/6 (33%)
		Ig strand F	317..322	CDD:409353	1/4 (25%)
		FN3	341..445	CDD:238020	26/129 (20%)
Igsf9	NP_001100667.1	IG_like	28..110	CDD:214653
		Ig strand B	37..41	CDD:409353
		Ig strand C	54..58	CDD:409353
		Ig strand E	91..95	CDD:409353
		IG_like	143..223	CDD:214653	19/103 (18%)
		Ig strand B	154..158	CDD:409353	0/3 (0%)
		Ig strand C	167..171	CDD:409353	0/3 (0%)
		Ig strand E	189..193	CDD:409353	2/8 (25%)
		Ig strand F	203..208	CDD:409353	2/4 (50%)
		Ig strand G	216..219	CDD:409353	0/2 (0%)
		Ig_3	226..305	CDD:464046	18/78 (23%)
		Ig	322..407	CDD:472250	5/84 (6%)
		Ig strand B	333..344	CDD:409353	0/10 (0%)
		Ig strand C	353..358	CDD:409353	0/4 (0%)
		Ig strand E	378..382	CDD:409353	0/3 (0%)
		Ig strand F	392..397	CDD:409353	0/4 (0%)
		Ig	418..503	CDD:472250	20/109 (18%)
		Ig strand B	436..440	CDD:409353	0/3 (0%)
		Ig strand C	449..453	CDD:409353	0/3 (0%)
		Ig strand E	469..473	CDD:409353	1/3 (33%)
		Ig strand F	483..488	CDD:409353	1/4 (25%)
		Ig strand G	496..499	CDD:409353	0/2 (0%)
		FN3	508..599	CDD:238020	22/97 (23%)
		FN3	625..715	CDD:238020	3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	766..807
		PHA03247	<777..1062	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	819..846
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	869..895
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	942..979
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1016..1079
		PDZ-binding. /evidence=ECO:0000250	1177..1179