DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33543 and ncam1a

DIOPT Version :9

Sequence 1:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_009293555.1	Gene:	ncam1a / 30447	ZFINID:	ZDB-GENE-990415-31	Length:	1010	Species:	Danio rerio

Alignment Length:	306	Identity:	74/306 - (24%)
Similarity:	118/306 - (38%)	Gaps:	37/306 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LSLQPSTPSITHFVNESFIIFCQTV--QKDIDTKWRDPRGQTRENTKGRVHIEKKTTGLLALVFE 110
            :.:.|:...|:  |.||....|:.|  .|:||  |..|.|:.....:..:.|.|.......|...
Zfish    22 VEITPTQGEIS--VGESKFFLCEVVGDAKEID--WFAPNGEKLLPGRPDISISKTDESSSTLTIY 82

  Fly   111 HIALEDRGNWTCEVNGNRNGNRNVNVEREFLASFELLVNQKISFGKTEQVQSVREGRDAMVNCFV 175
            :..::..|.:.|.....         |:|...:..:.:.||::|......|...||.||.:.|.|
Zfish    83 NANVDHAGMYKCVAKSG---------EKESQGTIIVKIFQKLTFQYAPSPQEFNEGDDADIICDV 138

  Fly   176 EGMPAPEVSWLYNGEYINTVNSTKHNRLSNG-LYIRNVSQADAGEYTCRAMRITPTFSDSDQITI 239
            ...|.|.:.|.|....|......:...|||. |.||.:.:.|.|:|||....:.....|...|.:
Zfish   139 ISSPPPTIIWRYKKMRIQPETDVRLKVLSNNHLQIRGIKKTDEGDYTCEGRIMARGEIDLRVIKV 203

  Fly   240 LLRIQHKPHWFFNETLP---VQY------AYVGGAVNLSCDAMGEPPPSFTWLHNNKGIVGFNHR 295
            ::.:           ||   .:|      |.:..||.|:|.|.|.|.|:..|...|..:.. :.:
Zfish   204 IVNV-----------LPSIRTRYTELNATADINQAVTLACHADGYPEPTVKWARGNTELES-DEK 256

  Fly   296 IFVADYGATLQLQMKNASQFGDYKCKVANPLGMLERVIKLRPGPKP 341
            ..:.:.|:.|.::..|....|||||...|..|.....:.|....:|
Zfish   257 YSLNEDGSELTIKDVNKLDEGDYKCIARNKAGERSEEVTLNVFVQP 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	22/59 (37%)
		IG_like	256..336	CDD:214653	23/88 (26%)
		IGc2	263..327	CDD:197706	19/63 (30%)
		FN3	341..445	CDD:238020	1/1 (100%)
ncam1a	XP_009293555.1	Ig	20..112	CDD:299845	20/102 (20%)
		I-set	21..111	CDD:254352	20/101 (20%)
		IG_like	121..200	CDD:214653	24/78 (31%)
		IGc2	128..189	CDD:197706	22/60 (37%)
		Ig	208..301	CDD:299845	25/93 (27%)
		IG_like	219..298	CDD:214653	22/79 (28%)
		Ig	300..406	CDD:299845	1/3 (33%)
		IG_like	308..406	CDD:214653
		ig	413..498	CDD:278476
		IG_like	415..498	CDD:214653
		fn3	505..589	CDD:278470
		FN3	624..715	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810