Protein Alignment CG33543 and Cntn6

DIOPT Version :10

• Sequence 1: NP_001014458.3
• Gene: CG33543 / 3346207
• FlyBaseID: FBgn0053543
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_037357.1
• Gene: Cntn6 / 27256
• RGDID: 62008
• Length: 1028
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 106/520 - (20%)
• Similarity: 167/520 - (32%)
• Gaps: 167/520 - (32%)

  Fly    43 PPTPPLSLQPSTPSITHFVNESFIIFCQTVQ--KDI--------------DTKWRDPRGQTRENT 91
            ||||  .:|.:...:..:..:..:.|.:|:|  ||.              |..||...|..   .
  Rat   210 PPTP--LVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSP---M 269

  Fly    92 KGRVHIEKKTTGLLALVFEHIALEDRGNWTCEVNGNRNGNRNVNVEREFLASFELLVNQKISFGK 156
            .|:|   |.:.....|.......||.|.:.| |.||..| ||            |...|.|.:..
  Rat   270 PGKV---KYSNSQATLEIPKFQQEDEGFYEC-VAGNLRG-RN------------LAKGQLIFYAP 317

  Fly   157 TEQVQSVREG----RDAMV-NCFVEGMPAPEVSWLYNGEYINTVNSTKHNRLSNG-LYIRNVSQA 215
            .|..|.::..    .|::. .|...|.|.|..:||.|||.:||   .:..:..|| |.|..::.:
  Rat   318 PEWEQKIQNTYLSIYDSLFWECKASGNPNPSYTWLKNGERLNT---EERIQTENGTLIITMLNVS 379

  Fly   216 DAGEYTCRAMRITPTFSDSDQITILLRIQHKPHWFFNETLPVQYAYVGGAVNLSCDAMGEPPPSF 280
            |:|.|.|.|.....|...:.::.:|   ...|.:..|....:....|||.:::.|.....|..|.
  Rat   380 DSGIYQCAAENKYQTIYANAELRVL---ASAPDFSKNPIKKISVVQVGGDISIECKPNAFPKASI 441

  Fly   281 TWLHNNKGIVGFNHRIFVADYGATLQLQMKNASQFGDYKCKVANPLG---------MLERVIKLR 336
            :|....:.:.. :.|:|..:.| :|::.....|..|.|.|...|..|         :.||.:...
  Rat   442 SWKRGTENLKQ-SKRVFFLEDG-SLKICNVTRSDAGSYTCVATNQFGNGKSSGSLIVKERTVITV 504

  Fly   337 PGPK---PLG------------PRRFQLKKLYTNGFELDIQTPRMSNVSDEMQIYGYRVAYMSDT 386
            |..|   .:|            |....|...|.||..:|::    ..|:...:|.|..|..:...
  Rat   505 PPSKMDVTVGESIVLPCQVSHDPTMEVLFVWYFNGDVIDLK----KGVAHFERIGGESVGDLMIR 565

  Fly   387 EFKFSAGNWSYAKQRDFSFHGGKHFI----------------------------IPHLETNTTYL 423
            ..:..              |.||:..                            :.|:.:.|:.|
  Rat   566 NIQLG--------------HSGKYLCTVQTTLERLSAVADIIVRGPPGPPEDVKVEHISSTTSQL 616

  Fly   424 MRAASRNLAGLSDW-------SPVKVFT----TAAGCSW----------------------SPWL 455
                        .|       ||:::||    |.....|                      |||:
  Rat   617 ------------SWRPGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGQTYNATVIGLSPWV 669

  Fly   456  455
              Rat   670  669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	Ig	<71..>123	CDD:472250	15/67 (22%)
		Ig strand E	105..109	CDD:409353	1/3 (33%)
		Ig strand F	119..123	CDD:409353	0/3 (0%)
		Ig	153..239	CDD:472250	24/91 (26%)
		Ig strand B	169..173	CDD:409353	0/4 (0%)
		Ig strand C	182..186	CDD:409353	0/3 (0%)
		Ig strand E	205..209	CDD:409353	3/4 (75%)
		Ig strand F	219..224	CDD:409353	2/4 (50%)
		Ig strand G	232..235	CDD:409353	0/2 (0%)
		IG_like	256..336	CDD:214653	19/88 (22%)
		Ig strand B	266..270	CDD:409353	0/3 (0%)
		Ig strand C	279..283	CDD:409353	1/3 (33%)
		Ig strand E	302..309	CDD:409353	2/6 (33%)
		Ig strand F	317..322	CDD:409353	2/4 (50%)
		FN3	341..445	CDD:238020	22/154 (14%)
Cntn6	NP_037357.1	Ig	26..120	CDD:472250
		Ig strand B	46..50	CDD:409353
		Ig strand C	59..63	CDD:409353
		Ig strand E	82..86	CDD:409353
		Ig strand F	97..102	CDD:409353
		Ig strand G	111..114	CDD:409353
		Ig	129..214	CDD:472250	4/5 (80%)
		Ig strand B	140..144	CDD:409353
		Ig strand C	154..158	CDD:409353
		Ig strand E	179..183	CDD:409353
		Ig strand F	193..198	CDD:409353
		Ig strand G	209..212	CDD:409353	1/1 (100%)
		Ig	227..315	CDD:472250	26/107 (24%)
		Ig strand B	245..249	CDD:409353	0/3 (0%)
		Ig strand C	258..262	CDD:409353	1/3 (33%)
		Ig strand E	280..284	CDD:409353	1/3 (33%)
		Ig strand F	294..299	CDD:409353	1/5 (20%)
		Ig strand G	307..310	CDD:409353	1/2 (50%)
		Ig	319..403	CDD:472250	24/86 (28%)
		Ig strand B	335..339	CDD:143205	0/3 (0%)
		Ig strand C	348..352	CDD:143205	0/3 (0%)
		Ig strand E	369..373	CDD:143205	2/3 (67%)
		Ig strand F	383..388	CDD:143205	2/4 (50%)
		Ig strand G	396..399	CDD:143205	0/2 (0%)
		Ig5_Contactin	408..496	CDD:409358	19/89 (21%)
		Ig strand A	408..413	CDD:409358	1/4 (25%)
		Ig strand A'	416..421	CDD:409358	0/4 (0%)
		Ig strand B	425..432	CDD:409358	1/6 (17%)
		Ig strand C	440..444	CDD:409358	1/3 (33%)
		Ig strand D	458..461	CDD:409358	0/2 (0%)
		Ig strand E	462..467	CDD:409358	2/5 (40%)
		Ig strand F	475..483	CDD:409358	3/7 (43%)
		Ig strand G	489..496	CDD:409358	0/6 (0%)
		Ig	500..598	CDD:472250	16/115 (14%)
		Ig strand B	517..521	CDD:409353	0/3 (0%)
		Ig strand C	532..536	CDD:409353	1/3 (33%)
		Ig strand E	560..564	CDD:409353	0/3 (0%)
		Ig strand F	574..579	CDD:409353	1/4 (25%)
		Ig strand G	587..590	CDD:409353	0/2 (0%)
		FN3	598..691	CDD:238020	13/84 (15%)
		FN3	<620..>912	CDD:442628	9/50 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	887..908
		FN3	903..983	CDD:214495