Protein Alignment CG33543 and Cntn4

DIOPT Version :10

• Sequence 1: NP_001014458.3
• Gene: CG33543 / 3346207
• FlyBaseID: FBgn0053543
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001103219.1
• Gene: Cntn4 / 269784
• MGIID: 1095737
• Length: 1026
• Species: Mus musculus
• Alignment Length: 460
• Identity: 106/460 - (23%)
• Similarity: 159/460 - (34%)
• Gaps: 97/460 - (21%)

  Fly    43 PPTPPLSLQPST-----PSITHFVNESFIIFCQTVQKDIDTK----------------WRDPRGQ 86
            ||||.:......     |.|.       :.|.:||..:..|.                ||...|:
Mouse   208 PPTPLILRNDGVMGEYEPKIE-------VQFPETVPAEKGTTVKLECFALGNPVPTILWRRADGK 265

  Fly    87 TRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCEVNGNRNGNRNVNVEREFLASFELLVNQK 151
            .... |.|.|   |:.|:|.:  .:...||.|::.|....:|..|              :...|.
Mouse   266 PIAR-KARRH---KSNGILEI--PNFQQEDAGSYECVAENSRGKN--------------VAKGQL 310

  Fly   152 ISFGKTEQVQSVREGRDAMV-----NCFVEGMPAPEVSWLYNGEYINTVNSTKHNRLSNGLYIRN 211
            ..:.:...||.:.:...||.     .|...|.|.|...||.||:.:.|.:..:..:.:..:.|.|
Mouse   311 TFYAQPNWVQIINDIHVAMEESVFWECKANGRPKPTYRWLKNGDPLLTRDRIQIEQGTLNITIVN 375

  Fly   212 VSQADAGEYTCRAMRITPTFSDSDQITILLRIQHKPHWFFNETL--PVQYAYVGGAVNLSCDAMG 274
            :|  |||.|.|.|.........|.::::   |...|.  |:.||  .|....|||.|.:.|....
Mouse   376 LS--DAGMYQCVAENKHGVIFSSAELSV---IAESPD--FSRTLLKRVTLVKVGGEVVIECKPKA 433

  Fly   275 EPPPSFTWLHNNKGIVGFNHRIFVADYGATLQLQMKNASQFGDYKCKVANPLGMLE---RVIKLR 336
            .|.|.:|| ...:.|:..|.||.:::.| .|::.....|..|.|.|...|..|...   .||...
Mouse   434 SPRPVYTW-RKGREILRENERITISEDG-NLRIINVTKSDAGSYTCIATNHFGTASSTGNVIVKD 496

  Fly   337 PGPKPLGPRRFQ--------LKKLYTNGFELDIQTPRMSNVSDEMQIYGYRVAYMSDTEFKFSAG 393
            |....:.|....        |....|:...|||......|        |:.:.:..|.:.....|
Mouse   497 PTKVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWTFN--------GHLIDFDKDGDHFERVG 553

  Fly   394 NWSYAKQ---RDFSF-HGGKHFIIPHLETNTTYLMRAASRNLAGLSDWSPVKVFT------TAAG 448
            ....|..   |:... |.||:..:  ::|:...|..||...:.|..  .|.:..|      |.|.
Mouse   554 GQDSAGDLMIRNIQLKHAGKYVCM--VQTSVDKLSVAADLIVRGPP--GPPEAVTIDEITDTTAQ 614

  Fly   449 CSWSP 453
            .||.|
Mouse   615 LSWRP 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33543	NP_001014458.3	Ig	<71..>123	CDD:472250	15/67 (22%)
		Ig strand E	105..109	CDD:409353	1/3 (33%)
		Ig strand F	119..123	CDD:409353	0/3 (0%)
		Ig	153..239	CDD:472250	23/90 (26%)
		Ig strand B	169..173	CDD:409353	2/8 (25%)
		Ig strand C	182..186	CDD:409353	0/3 (0%)
		Ig strand E	205..209	CDD:409353	0/3 (0%)
		Ig strand F	219..224	CDD:409353	2/4 (50%)
		Ig strand G	232..235	CDD:409353	0/2 (0%)
		IG_like	256..336	CDD:214653	24/82 (29%)
		Ig strand B	266..270	CDD:409353	1/3 (33%)
		Ig strand C	279..283	CDD:409353	1/3 (33%)
		Ig strand E	302..309	CDD:409353	2/6 (33%)
		Ig strand F	317..322	CDD:409353	2/4 (50%)
		FN3	341..445	CDD:238020	22/121 (18%)
Cntn4	NP_001103219.1	Ig	25..120	CDD:472250
		Ig strand B	46..50	CDD:409353
		Ig strand C	59..63	CDD:409353
		Ig strand E	82..86	CDD:409353
		Ig strand F	97..102	CDD:409353
		Ig strand G	111..114	CDD:409353
		Ig	129..213	CDD:472250	4/4 (100%)
		Ig strand B	140..144	CDD:409353
		Ig strand C	154..158	CDD:409353
		Ig strand E	177..181	CDD:409353
		Ig strand F	191..196	CDD:409353
		Ig strand G	207..210	CDD:409353	1/1 (100%)
		Ig	225..313	CDD:472250	22/114 (19%)
		Ig strand B	243..247	CDD:409353	0/3 (0%)
		Ig strand C	256..260	CDD:409353	0/3 (0%)
		Ig strand E	278..282	CDD:409353	2/3 (67%)
		Ig strand F	292..297	CDD:409353	1/4 (25%)
		Ig strand G	305..308	CDD:409353	0/2 (0%)
		Ig	318..401	CDD:472250	23/84 (27%)
		Ig strand B	333..337	CDD:409353	0/3 (0%)
		Ig strand C	346..350	CDD:409353	0/3 (0%)
		Ig strand E	367..371	CDD:409353	0/3 (0%)
		Ig strand F	381..386	CDD:409353	2/4 (50%)
		Ig strand G	394..397	CDD:409353	0/2 (0%)
		Ig	406..494	CDD:472250	27/91 (30%)
		Ig strand B	425..429	CDD:409353	1/3 (33%)
		Ig strand C	438..442	CDD:409353	2/4 (50%)
		Ig strand E	460..464	CDD:409353	2/4 (50%)
		Ig strand F	474..479	CDD:409353	2/4 (50%)
		Ig strand G	487..490	CDD:409353	0/2 (0%)
		Ig6_Contactin-4	496..597	CDD:409439	21/110 (19%)
		Ig strand A	496..502	CDD:409439	1/5 (20%)
		Ig strand A'	505..510	CDD:409439	0/4 (0%)
		Ig strand B	513..521	CDD:409439	1/7 (14%)
		Ig strand C	530..534	CDD:409439	0/3 (0%)
		Ig strand D	555..558	CDD:409439	0/2 (0%)
		Ig strand E	559..563	CDD:409439	0/3 (0%)
		Ig strand F	572..579	CDD:409439	2/8 (25%)
		FN3	580..>1014	CDD:442628	12/42 (29%)
		Ig strand G	586..590	CDD:409439	1/3 (33%)
		FN3	597..690	CDD:238020	7/25 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	685..710
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	886..906