DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33543 and Ntm

DIOPT Version :9

Sequence 1:NP_001014458.3 Gene:CG33543 / 3346207 FlyBaseID:FBgn0053543 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:286 Identity:62/286 - (21%)
Similarity:116/286 - (40%) Gaps:53/286 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 FVNESFIIFCQTVQKDIDTKW-RDPRGQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCE 123
            ::|.|.|::..      :.|| .|||.....||:.:..||          .:::.:.|.|.:||.
Mouse    68 WLNRSTILYAG------NDKWCLDPRVVLLSNTQTQYSIE----------IQNVDVYDEGPYTCS 116

  Fly   124 VNGNRNGNRNVNVEREFLASFELLVNQKISFGKTEQVQSVREGRDAMVNCFVEGMPAPEVSWLY- 187
            |..:.:..         .:...|:|.......:.....|:.||.:..:.|...|.|.|.|:|.: 
Mouse   117 VQTDNHPK---------TSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHI 172

  Fly   188 NGEYINTVNSTKHNRLSNGLYIRNVSQADAGEYTCRAMRITPTFSDSDQITILLRIQHKPHW--F 250
            :.:.:..|:..::      |.|:.:::..:|||.|.|       |:.....::.|::...::  :
Mouse   173 SPKAVGFVSEDEY------LEIQGITREQSGEYECSA-------SNDVAAPVVRRVKVTVNYPPY 224

  Fly   251 FNET----LPVQYAYVGGAVNLSCDAMGEPPPSFTWLHNNKGIVGFNHRIFVADYGATLQLQMKN 311
            .:|.    :|     ||....|.|:|...|...|.|..::|.:|.....:.|.:.....:|...|
Mouse   225 ISEAKGTGVP-----VGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVENRPFLSKLTFFN 284

  Fly   312 ASQ--FGDYKCKVANPLGMLERVIKL 335
            .|:  :|:|.|..:|.||.....|.|
Mouse   285 VSEHDYGNYTCVASNKLGHTNASIML 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33543NP_001014458.3 IGc2 165..224 CDD:197706 15/59 (25%)
IG_like 256..336 CDD:214653 23/82 (28%)
IGc2 263..327 CDD:197706 17/65 (26%)
FN3 341..445 CDD:238020
NtmNP_001344522.1 Ig 44..132 CDD:416386 18/88 (20%)
Ig strand A' 44..49 CDD:409353
Ig strand B 51..59 CDD:409353
CDR1 59..63 CDD:409353
FR2 64..70 CDD:409353 0/1 (0%)
Ig strand C 64..70 CDD:409353 0/1 (0%)
CDR2 71..83 CDD:409353 3/17 (18%)
Ig strand C' 72..76 CDD:409353 2/3 (67%)
Ig strand C' 80..83 CDD:409353 1/2 (50%)
FR3 84..118 CDD:409353 11/43 (26%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 2/15 (13%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 1/17 (6%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 17/81 (21%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 1/8 (13%)
Ig strand F 197..205 CDD:409353 5/14 (36%)
Ig_3 222..299 CDD:404760 19/81 (23%)
putative Ig strand A 223..229 CDD:409353 1/5 (20%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 1/3 (33%)
Ig strand E 278..282 CDD:409353 1/3 (33%)
Ig strand F 292..297 CDD:409353 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833607
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
32.790

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