DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33543 and Dscam

DIOPT Version :9

Sequence 1:NP_001014458.3 Gene:CG33543 / 3346207 FlyBaseID:FBgn0053543 Length:468 Species:Drosophila melanogaster
Sequence 2:XP_006522949.1 Gene:Dscam / 13508 MGIID:1196281 Length:2034 Species:Mus musculus


Alignment Length:464 Identity:117/464 - (25%)
Similarity:179/464 - (38%) Gaps:94/464 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 NAAILGQLDSTSSGGSGTGGAPPDRPPTPPLSLQP-STPSITHFVNESFIIFCQTVQKD--IDTK 79
            |..:..|| |||.....|...||        .:|| ..|..:  :.:...|.|..|..|  |...
Mouse   576 NVLVQPQL-STSQSVHVTVKVPP--------FIQPFEFPRFS--IGQRVFIPCVVVSGDLPITIT 629

  Fly    80 W-RDPR------GQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCEVNGNRNGNRNVNVE 137
            | :|.|      |.|.:|      |:..:    :|...:::|...||:||...     |....||
Mouse   630 WQKDGRPIPASLGVTIDN------IDFTS----SLRISNLSLMHNGNYTCIAR-----NEAAAVE 679

  Fly   138 REFLASFELLVNQKISFGKTEQVQSVREGRDAMVNCFVEGMPAPEVSWLYN-GEYINTVNSTKHN 201
            .:    .:|:|.....|....:.|....|:..::||..||.|.|.:.|.:: |..:........|
Mouse   680 HQ----SQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALN 740

  Fly   202 R----LSNG-LYIRNVSQADAGEYTCRAMR-ITPTFSDSDQITILL--RIQHKPHWFFNETLPVQ 258
            .    |||| |.|::|.:.|:|.|.|:... :....|.|..:|:.:  .|...|    |.||..|
Mouse   741 GRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYP----NTTLATQ 801

  Fly   259 YAYVGGAVNLSCDAMGEPPPSFTWLHNNKGIVGFNHRIFVA--DYG----ATLQLQMKNASQFGD 317
                |....:||.|.||.|....|...::.|.....|..|:  :.|    :|||:........|.
Mouse   802 ----GQRKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 862

  Fly   318 YKCKVANPLGMLERVIKLRPGPKPLGPRRFQLKKL--------YTNGFELDIQTPRMSNVSDEMQ 374
            :.|...|..|....:|:|.. .:|..|...::|.:        :|.||  |..:|          
Mouse   863 FSCHAINSYGEDRGIIQLTV-QEPPDPPEIEIKDVKARTITLRWTMGF--DGNSP---------- 914

  Fly   375 IYGYRVAYMSDTEFKFSAGNWSYAKQ-RDFSFHGGKHFIIPHLETNTTYLMRAASRNLAGLSDWS 438
            |.||      |.|.|..:.:|..|:: :|.|.......|| .:..::||.:|..::|..|.|:  
Mouse   915 ITGY------DIECKNKSDSWDSAQRTKDVSPQLNSATII-DIHPSSTYSIRMYAKNRIGKSE-- 970

  Fly   439 PVKVFTTAA 447
            |....|..|
Mouse   971 PSNEITITA 979

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33543NP_001014458.3 IGc2 165..224 CDD:197706 21/64 (33%)
IG_like 256..336 CDD:214653 21/85 (25%)
IGc2 263..327 CDD:197706 18/69 (26%)
FN3 341..445 CDD:238020 27/112 (24%)
DscamXP_006522949.1 Ig 15..115 CDD:386229
IGc2 239..300 CDD:197706
IG 320..400 CDD:214652
Ig_3 410..488 CDD:372822
IGc2 518..575 CDD:197706
Ig 596..686 CDD:386229 27/118 (23%)
Ig_DSCAM 707..784 CDD:143211 22/76 (29%)
Ig 802..889 CDD:386229 22/87 (25%)
FN3 885..978 CDD:238020 28/113 (25%)
FN3 986..1083 CDD:238020
FN3 1091..1184 CDD:238020
FN3 1189..1278 CDD:238020
Ig_3 1301..1363 CDD:372822
FN3 1380..1470 CDD:238020
FN3 1486..1555 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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